Results 71 to 80 of about 3,560,399 (311)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
EAI Endorsed Transactions on Energy WebTo solve the problem of complex and difficult to quantify factors affecting investment returns and risks in clean energy power grids, this study comprehensively applies the interpretive structural model and Monte Carlo model to the analysis of ...
Shu Li, Junyong Xiang, Rong Li, Duo Wang
doaj +1 more source
Metals, 2020 Friction and wear performance of austenite stainless steels have been extensively studied and show a close relationship with the friction-induced martensitic transformation.
Bo Mao, Shuangjie Chu, Shuyang Wang
doaj +1 more source
Multiple Access Channels with Combined Cooperation and Partial Cribbing
, 2014 In this paper we study the multiple access channel (MAC) with combined cooperation and partial cribbing and characterize its capacity region. Cooperation means that the two encoders send a message to one another via a rate-limited link prior to ...
Kopetz, Tal +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Factors shaping innovation cooperation between companies and research and development institutions exemplified by the case of south-western Poland [PDF]
, 2013 The aim of this paper is the presentation of the probit models analysis factors shaping innovation cooperation between companies and research. The practical issue is exemplified by the case of south –western Poland.
Tomaszewski, Marek
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Статистика и экономика, 2016 The article considers the General scheme of the modeling process of marketing theinnovation pillar, is an attempt to summarize and systematize approaches tomodel building innovative capacity of organizations on the basis of the marketingconcept, the ...
Anna A. Aletdinova, Yuliya A. Makurina
doaj +1 more source
Cooperation in effective action [PDF]
, 2006 The ability to cooperate in collective action problems — such as those relating to the use of common property resources or the provision of local public goods — is a key determinant of economic performance.
Bandiera, O., Barankay, I., Rasul, I.
core
Journal of Economic Perspectives, 1988 Much economic analysis -- and virtually all game theory -- starts with the assumption that people are both rational and selfish. The predictions derived from this assumption of rational selfishness are, however, violated in many familiar contexts. In this column and the next one, the evidence from laboratory experiments is examined to see what has been
Dawes, Robyn M, Thaler, Richard H
openaire +1 more source