Results 71 to 80 of about 1,180,485 (310)

Evaluation of Sida’s Model for Bilateral Research Cooperation

open access: yes, 2020
The purpose of the evaluation is to provide an overall assessment of the extent to which Sida’s model for bilateral research cooperation builds research capacity in low-income countries. The assessment will serve as input to the in-depth review for
Chou, Panith   +7 more
core  

COMPULSORY COOPERATION AND COINCIDENTAL COOPERATION

open access: yesJournal of Positive Management, 2011
The aim of the article is to prove that companies cooperate not only because they wish to, but also because they are forced to do it. Moreover, It turns out that sometimes firms cooperate in strategic alliances with partners which were not selected, but appeared coincidentally.
openaire   +5 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Risk-return analysis of clean energy grid project investment based on integrated ISM and Monte Carlo model

open access: yesEAI Endorsed Transactions on Energy Web
To solve the problem of complex and difficult to quantify factors affecting investment returns and risks in clean energy power grids, this study comprehensively applies the interpretive structural model and Monte Carlo model to the analysis of ...
Shu Li, Junyong Xiang, Rong Li, Duo Wang
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Cooperation Through Rational Investments in Social Organization

open access: yes
Repeated interactions and contractual agreements are examples of different ways of organizing interactions in social and economic life and can foster cooperation in social dilemmas.
Anna Sokolova (Utrecht University)
core   +2 more sources

High-tech agricultural tools as a determinant of dynamic rationalization of business processes in Russian agriculture [PDF]

open access: yesBIO Web of Conferences
In the current environment of innovative transformations in the Russian Federation, there is a significant expansion of digital technological products, and there is an active digital optimization of business processes in all national economic sectors ...
Moroz Oksana, Medvedsky Dmitriy
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Liver protects neuron viability and electrocortical activity in post-cardiac arrest brain injury

open access: yesEMBO Molecular Medicine
Brain injury is the leading cause of mortality among patients who survive cardiac arrest (CA). Clinical studies have shown that the presence of post-CA hypoxic hepatitis or pre-CA liver disease is associated with increased mortality and inferior ...
Zhiyong Guo   +23 more
doaj   +1 more source

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