Results 61 to 70 of about 133,710 (277)

New Species, New Record, and Antagonistic Potential of Torula (Torulaceae, Pleosporales) from Jilin Province, China

Microorganisms
During a survey of ascomycetous fungi associated with plant litter and submerged wood in Jilin Province, China, two hyphomycetous fungi were discovered. Morphological examination and molecular phylogenetic analyses revealed that these isolates represent ...
Rong Xu, Yue Zhang, Wenxin Su, Yu Li
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The Human Family—Its Evolutionary Context and Diversity

Social Sciences, 2021
The family defines many aspects of our daily lives, and expresses a wide array of forms across individuals, cultures, ecologies and time. While the nuclear family is the norm today in developed economies, it is the exception in most other historic and ...
Karen L. Kramer
doaj   +1 more source

On the further integration of cooperative breeding and cooperation theory [PDF]

Behavioural Processes, 2007
We present a synopsis about the commentaries to the target article "Integrating cooperative breeding into theoretical concepts of cooperation", in which we attempted to integrate general mechanisms to explain cooperative behaviour among unrelated individuals with classic concepts to explain helping behaviour in cooperative breeders that do not invoke ...
Bergmüller, Ralph, Russell, Andrew F., Johnstone, Rufus A., Bshary, Redouan   +3 more
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Family living: an overlooked but pivotal social system to understand the evolution of cooperative breeding [PDF]

, 2017
Bird breeding systems are more diverse than previously appreciated. Here we show that defining an intermediate breeding system, family breeding, where individuals postpone their dispersal but do not cooperate in reproduction, is a natural extension of ...
Drobniak, Szymon M., Griesser, Michael, Mourocq, Emeline, Wagner, Gretchen   +3 more
core  

Cooperative problem solving in a cooperatively breeding primate (Saguinus oedipus) [PDF]

Animal Behaviour, 2005
We investigated cooperative problem solving in unrelated pairs of the cooperatively breeding cottontop tamarin, Saguinus oedipus, to assess the cognitive basis of cooperative behaviour in this species and to compare abilities with other apes and monkeys.
Katherine A, Cronin, Aimee V, Kurian, Charles T, Snowdon   +2 more
openaire   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Heterologous expression of FTO in latex enhances rubber content by modulating the mRNA stability in the rubber biosynthesis pathway

Industrial Crops and Products
RNA N6-methyladenosine (m6A) modification plays a significant role in plant development and stress tolerance. However, m6A atlas and functions in natural rubber (NR) production remain unexplored in rubber-producing plants.
Yingchao Tan, Yuan Yao, Xue Yang, Xue Li, Jing Ning, Chao Zhang, Cheng Zheng, Jiyan Qi, De Ye, Jie Cao, Chaorong Tang, Kaiye Liu   +11 more
doaj   +1 more source