Results 61 to 70 of about 4,116,524 (296)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Dynamic traffic signal control using mean field multi‐agent reinforcement learning in large scale road‐networks

IET Intelligent Transport Systems, 2023
Multi‐agent reinforcement learning has played an increasingly important role in intelligent traffic signal control due to its self‐learning ability. However, existing algorithms only focus on signal timing mechanism design while ignoring the exponential ...
Tianfeng Hu, Zhiqun Hu, Zhaoming Lu, Xiangming Wen   +3 more
doaj   +1 more source

Cooperative communication based connectivity recovery for UAV networks [PDF]

ACM Turing Celebration Conference, 2018
UAV networks often partition into separated clusters due to the high node and link dynamic. As a result, network connectivity recovery is an important issue in this area.
Stella Wen Tian, Zhenzhen Jiao, Min Liu, Meng Zhang, Dong Li   +4 more
semanticscholar   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Harvest-Then-Cooperate: Wireless-Powered Cooperative Communications [PDF]

IEEE Transactions on Signal Processing, 2015
In this paper, we consider a wireless-powered cooperative communication network consisting of one hybrid access-point (AP), one source, and one relay. In contrast to conventional cooperative networks, the source and relay in the considered network have no embedded energy supply.
He Chen 0001, Yonghui Li 0001, João Luiz Rebelatto, Bartolomeu F. Uchôa Filho, Branka Vucetic   +4 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Comprehensive Performance Analysis of Fully Cooperative Communication in WBANs

IEEE Access, 2016
While relay-based cooperative networks (widely known in the literature as cooperative communication), where relays only forward signals from the sources to the destination, have been extensively researched, fully cooperative systems have not been ...
L. C. Tran, A. Mertins, X. Huang, F. Safaei   +3 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source