Results 41 to 50 of about 890,943 (281)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Channel-Aware Energy-Efficient Two-Hop Cooperative Routing Protocol for Underwater Acoustic Sensor Networks

IEEE Access, 2019
This paper sought to investigate the performance of multi-hop underwater acoustic sensor networks (UW-ASNs) when they deploy cooperative routing algorithms combining the cooperative communication and routing methods. Taking into account energy efficiency,
Hoa Tran-Dang, Dong-Seong Kim
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Performance Analysis of Wireless Cooperative Networks with Iterative Incremental Relay Selection [PDF]

AUT Journal of Electrical Engineering, 2017
In this paper, an iterative incremental relay selection (IIRS) scheme is considered for wireless cooperative networks in order to increase the reliability of transmission.
S. Poursajadi, M. H. Madani
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Dynamic traffic signal control using mean field multi‐agent reinforcement learning in large scale road‐networks

IET Intelligent Transport Systems, 2023
Multi‐agent reinforcement learning has played an increasingly important role in intelligent traffic signal control due to its self‐learning ability. However, existing algorithms only focus on signal timing mechanism design while ignoring the exponential ...
Tianfeng Hu, Zhiqun Hu, Zhaoming Lu, Xiangming Wen   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Performance analysis of multi-relay DF cooperative communication system based on directional antenna

Dianxin kexue, 2016
In order to achieve reliable communication in multi-relay cooperative communication，the directional antenna combining multi-relay cooperative communication system and optimal relay selection decode-and-forward cooperative strategy was presented.Firstly ...
Mingwei WANG, Huisheng ZHANG, Lixin LI, Lifeng HE   +3 more
doaj   +2 more sources

Joint time and power allocation for uplink cooperative non-orthogonal multiple access based massive machine-type communication Network

International Journal of Distributed Sensor Networks, 2018
Non-orthogonal multiple access is an essential promising solution to support large-scale connectivity required by massive machine-type communication scenario defined in the fifth generation (5G) mobile communication system.
Shujun Han, Xiaodong Xu, Litong Zhao, Xiaofeng Tao   +3 more
doaj   +1 more source