Results 71 to 80 of about 349,390 (311)
On the logic of cooperation and propositional control
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Wiebe van der Hoek +1 more
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Zeolite adsorbents were synthesized through an alkali fusion-hydrothermal process, using coal fly ash as a raw material. Firstly, the coal fly ash was mixed with sodium hydroxide at a mass ratio of 1∶1.2 and then roasted at 850 ℃ for 2 h to obtain the ...
Zhuo CHEN +7 more
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Joint Analysis of the Commuting Departure Time and Travel Mode Choice: Role of the Built Environment
This paper aims to conduct an empirical study to evaluate the influence of built environment features and socioeconomic factors on commuters’ simultaneous choice of departure time and travel mode.
Xiaolei Ma +4 more
doaj +1 more source
2021 Home Grounds and Animals PMG - Author Contact List
This is a chapter of the 2021 Home Grounds and Animals PMG. This 2021 Virginia Pest Management Guide provides the latest recommendations for controlling diseases, insects, and weeds for home grounds and animals.
Wycoff, Stephanie B. +19 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Per- and polyfluoroalkyl substances (PFAS), particularly the legacy compounds Perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), are globally ubiquitous persistent organic pollutants that pose significant health risks. Although these
Xiaolong Wu +3 more
doaj +1 more source
The utilization of microalgae for bioremediation presents a highly promising and cost-effective approach, offering advantages of simultaneous pollutant removal and biomass recovery.
Lifeng Wang +4 more
doaj +1 more source
Analytical Model of Spread of Epidemics in Open Finite Regions
Epidemic dynamics, a kind of biological mechanisms describing microorganism propagation within populations, can inspire a wide range of novel designs of engineering technologies, such as advanced wireless communication and networking, global immunization
Daxin Tian +4 more
doaj +1 more source

