Results 81 to 90 of about 297,738 (268)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Current Situation and Development Trend of End-of-life Photovoltaic Module Treatment and Disposal
能源环境保护The adoption of clean energy, particularly solar energy, serves as a critical measure for achieving the dual-carbon goals. By the end of 2023, China′s cumulative installed solar capacity had reached 609 GW, with projections indicating a rise to ...
Shifa ZHOU +7 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Control of kinetics by cooperative interactions [PDF]
IUBMB Life, 2011 AbstractCooperative effects in ligand binding and dissociation kinetics are much less investigated than steady state kinetics or equilibrium binding. Nevertheless, cooperativity in ligand binding leads necessarily to characteristic properties with respect to kinetic properties of the system.
openaire +2 more sources
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
能源环境保护With China′s "dual carbon" goals continuously deepening, the wind power and photovoltaic industries are experiencing steady growth, with the new energy vehicle sector rapidly developing.
Qingfang ZOU +4 more
doaj +1 more source
Cooperative Control Of Electronic Power Processors In Micro-grids
Eletrônica de Potência, 2009 Micro-grids offer a new challenging domain for power electronics, since they include a variety of power sources and electronic power processors (EPP) interacting each other.
Elisabetta Tedeschi +3 more
doaj +1 more source
Modeling and Optimization of Connected and Automated Vehicle Platooning Cooperative Control with Measurement Errors. [PDF]
Sensors (Basel), 2023 Luo W, Li X, Hu J, Hu W.
europepmc +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Journal of Advanced Transportation, 2018 Exploring travel time distribution and variability patterns is essential for reliable route choices and sophisticated traffic management and control. State-of-the-art studies tend to treat different types of roads equally, which fails to provide more ...
Peng Chen +3 more
doaj +1 more source