Results 81 to 90 of about 563,494 (333)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Novel opportunistic cooperative multicast scheme for NOMA
Tongxin xuebao, 2020 The cognitive radio technology was applied to non-orthogonal multiple access (NOMA) cooperative multicast system,the feasibility of using users as relays was studied,and a two-level cooperative transmission scheme with parameterized multicast candidate ...
Yin LU +3 more
doaj +2 more sources
A Simple Cooperative Diversity Method Based on Network Path Selection
, 2005 Cooperative diversity has been recently proposed as a way to form virtual antenna arrays that provide dramatic gains in slow fading wireless environments.
Bletsas Aggelos(http://users.isc.tuc.gr/~abletsas) +4 more
core +2 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Research on cognitive user pairing and cooperative sensing
Tongxin xuebao, 2012 Aim at the shortages of the cooperative algorithm in sensing and time slot spent,an optimal cognitive users pairing and cooperative sensing algorithm was proposed.To achieve the best sensing performance,the pairing criterion was adopted where the one ...
Zhi-hua BAO +3 more
doaj
Metric-Based Cooperative Routing in Multihop Ad Hoc Networks
Journal of Computer Networks and Communications, 2012 Cooperative communication fully leverages the broadcast nature of wireless channels and exploits time/spatial diversity in a distributed manner, thereby achieving significant improvements in system capacity and transmission reliability.
Xin He, Frank Y. Li
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A cooperative multicast efficient resource allocation scheme based on limited feedback
Dianxin kexue, 2017 A joint subcarrier and power allocation scheme based on limited feedback for cooperative multicast network was proposed to minimize the consumed power under constrain of QoS requirement.The new scheme worked in two steps.Firstly,subcarriers were ...
Lei CHEN
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source