Results 71 to 80 of about 67,451 (260)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Transmission capacity of wireless sensor networks based on cooperative diversity

四川大学学报. 自然科学版, 2016
This paper study the transmission capacity of wireless sensor networks based on the cooperative diversity technology. At first, the paper establish the cooperative diversity model for multi-source, multi-sink and multi-relay sensor networks, on which the
HU Jin-Li, YU Gen-Jian
doaj  

Interference Range-Reduced Cooperative Multiple Access with Optimal Relay Selection for Large Scale Wireless Networks

Sensors, 2019
Cooperative communication improves the link throughput of wireless networks through spatial diversity. However, it reduces the frequency reuse of the entire network due to the enlarged link interference range introduced by each helper.
Kai Liu, Rui Wang, Caizhao Yue, Feng Liu, Tao Lu, Zixiang Xiong   +5 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Methanol-based biosynthesis of p-coumaric acid by engineered Pichia pastoris

Bioresources and Bioprocessing
p-Coumaric acid (p-CA) is a key aromatic precursor for the biosynthesis of flavonoids, stilbenoids, and other high-value phenylpropanoids. While microbial production of p-CA typically relies on sugar-based substrates, methanol offers a sustainable and ...
Mengyuan Chen, Jiayu Fang, Shuxian Wang, Guoxia Liu, Yanping Zhang, Yin Li, Kaizhi Jia, Taicheng Zhu   +7 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

The Rural Cooperative in China under the Governance of the Christ Ethic Value

SHS Web of Conferences, 2014
Based on the analysis on the basic information, problems and characters of rural cooperative in China, the paper finds that the cooperative governance by the blood, institution should be changed into the governance by civil ethic. We compare the relation
Xiliang Wu
doaj   +1 more source

Exploiting Sparsity in Amplify-and-Forward Broadband Multiple Relay Selection

IEEE Access, 2019
Cooperative communication has attracted significant attention in the last decade due to its ability to increase the spatial diversity order with only single-antenna nodes.
Ala Gouissem, Ridha Hamila, Naofal Al-dhahir, Sebti Foufou   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source