Results 51 to 60 of about 2,869,505 (336)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

UKRAINIAN AGRICULTURAL COOPERATION IN THE BACKGROUND OF THE REVOLUTIONARY CONSUMPTION OF THE EARLY 20TH CENTURY

open access: yesУкраїнський селянин, 2019
The article reveals the regularities and peculiarities of the development of Ukrainian agricultural cooperation during the first two decades of the twentieth century.
A. Morozov, N. Pavlova
doaj  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The Romanian Agriculture Cooperative Movement, from the Beginning to the Threshold of the Second World War. Briefly Historic Argument or Argument for History [PDF]

open access: yesTheoretical and Applied Economics, 2007
In the philosophical meaning, the cooperative is a result of the knowing experimentallydevelopment and includes the interaction between: persons of consequence – through ideas and attitudes,state – through laws and institutes, experiences – through ...
Gabriel Popescu, Florentina Constantin
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Characteristics of the Human Arm Based on a Musculoskeletal Model of Cooperative Motion between Two Humans

open access: yesJournal of Biomechanical Science and Engineering, 2008
In this study, we considered a single rotational degree-of-freedom experimental system, in addition to a mass-spring-damper-friction biomechanical model of the human arm, and then investigated master-slave and master-semi-master cooperative motions.
Nan ZHANG   +4 more
doaj   +1 more source

The Head Movement Cooperated with Mandibular Tapping Movement.

open access: yesNihon Hotetsu Shika Gakkai Zasshi, 1996
The purpose of this study was to confirm the existence of a rhythm for head movement during tapping movements, its coordination with jaw movements, and its functional significance.A system that simultaneously tracks head and jaw movements was used.Four normal adult males were selected as subjects.The jaw range of motion and tapping frequency were ...
openaire   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

The challenge of gender equity in coffee cooperatives

open access: yesCooperativismo y Desarrollo, 2022
Cooperativism is a movement which ideology is based on principles, values and standards of behavior that regulate and guide the relations of cooperative members.
Mindra Arévalo Zurita   +3 more
doaj  

Home - About - Disclaimer - Privacy