Results 221 to 230 of about 12,490 (287)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Intelligent Spectrum Sensing for NOMA Systems: A Cost-Sensitive LightGBM Approach with Objective-Driven Learning. [PDF]

Sensors (Basel)
Srisomboon K, Pipanmekaporn L, Prayote A, Lee W.   +3 more
europepmc   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Macrocycle-Assisted Cooperative Fe³⁺ Coordination and Fluorescence Regulation in a Coumarin-Functionalized Calix[4]arene. [PDF]

ACS Omega
Güngör Ö, Taşci N, Ünaldı AŞ, Durmuş M.   +3 more
europepmc   +1 more source

Effect of Alkyl Chain Length on the Bandgap, Ferroelectric, and Photoelectric Properties of Lead‐Based Molecular Ferroelectrics

Advanced Science, EarlyView.
This study develops a novel 2D molecular ferroelectric [C6N2H18]PbI4 with polarization enhanced photovoltaics. It systematically investigates the effect of alkylamine spacer cation chain lengths on the band gap, ferroelectric, and photoelectric properties, offering new design strategies.
Ganghua Zhang, Jinrong Wen, Ping Chen, Zhibo Chen, Pingying Tang, Dezeng Li, Jingshan Hou, Yongzheng Fang   +7 more
wiley   +1 more source

Infrared Imaging for Autonomous Power Inspection: A Review from Detector to System Integration. [PDF]

Sensors (Basel)
Guo Y, Du Y, Mao R, Zhao Y, Guo J.
europepmc   +1 more source

Synergistic PdMoCu Trimetallic Metallene-Enhanced Electrochemiluminescence Biosensor for Ultrasensitive Detection of Microcystin-LR. [PDF]

Biosensors (Basel)
Yang X, Wang L, Tu J, Li Y, Yang L, Gao Z.   +5 more
europepmc   +1 more source

Heteroatom-doped MXene quantum dots for selective transition metal ion sensing: from atomic-level design to intelligent and deployable platforms. [PDF]

RSC Adv
Daoud E, Imad Najm B, Salim Waleed O, Shukla MB, M M R, Sasikumar Y, Sharma V, Aldulaimi A, Smaeilpour S.   +8 more
europepmc   +1 more source

Advanced Sensors for Real-Time Monitoring Applications ‖. [PDF]

Sensors (Basel)
Korostynska O, Mason A.
europepmc   +1 more source