Results 71 to 80 of about 85,658 (276)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Research on SSDF Attack and Defense for Cooperative Spectrum Sensing

Dianxin kexue, 2014
Cooperative spectrum sensing is the core of cognitive radio technologies to utilize spectrum resources effectively. However, cooperative spectrum sensing schemes are vulnerable to abuses by false sensing data, and thus offering opportunities for ...
Jingyu Feng
doaj   +2 more sources

Energy detection based cooperative spectrum sensing system for emergency networks [PDF]

, 2017
During emergencies, a number of rescue teams come to the field and setup their own radio communication systems. If the deployed communication setup does not coordinate among themselves properly, they may interfere with each other when using the same RF ...
Hadi Fikri, A. H. A., Kamaludin Mohamad, Y., Paulson, E. N., Rashid, R. A., Sarijari, M. A.   +4 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Secure Cooperative Spectrum Sensing and Allocation in Distributed Cognitive Radio Networks

International Journal of Distributed Sensor Networks, 2015
Cognitive radio networks (CRNs) are an emerging wireless communications technique for resolving the significant spectrum scarcity problem. Despite their promising characteristics, CRNs also introduce new security threats, especially the internal attacks ...
Hui Lin, Jia Hu, Chuan Huang, Li Xu, Bin Wu   +4 more
doaj   +1 more source

Distributed Cooperative Sensing in Cognitive Radio Networks: An Overlapping Coalition Formation Approach

, 2014
Cooperative spectrum sensing has been shown to yield a significant performance improvement in cognitive radio networks. In this paper, we consider distributed cooperative sensing (DCS) in which secondary users (SUs) exchange data with one another instead
Han, Zhu, Saad, Walid, Song, Lingyang, Wang, Tianyu   +3 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

General analytical framework for cooperative sensing and access trade-off optimization

, 2014
In this paper, we investigate the joint cooperative spectrum sensing and access design problem for multi-channel cognitive radio networks. A general heterogeneous setting is considered where the probabilities that different channels are available, SNRs ...
Le, Long Bao, Tan, Le Thanh
core   +1 more source