Results 51 to 60 of about 12,490 (287)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Time-efficient cooperative spectrum sensing via analog computation over multiple-access channel [PDF]

open access: yes, 2017
Conventional cooperative spectrum sensing (CSS) schemes in cognitive radio networks (CRNs) require that the secondary users (SUs) report their sensing data separately in the time domain to the fusion center, which yields long reporting delay especially ...
Xu C(许驰)   +4 more
core  

Cooperative Spectrum Sensing Algorithm Based on the Relay [PDF]

open access: yes, 2011
Cooperative spectrum sensing is investigated in cognitive radio (CR) networks over Rayleigh fading channels. By utilizing the relay to enhance the reliability of the sensing information reporting, cooperative spectrum sensing algorithm based on the relay
Juan Chen   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Multi-threshold Cooperative Spectrum Detection Algorithm Based on Weight Clustering [PDF]

open access: yesJisuanji gongcheng, 2018
Cooperative spectrum sensing algorithm requires a control channel when detecting the spectrum of primary user.However,the limitation of control channel bandwidth is the bottleneck of application of cooperative spectrum sensing when the number of ...
PENG Junwei,HAN Zhiren,PENG Kaizhi
doaj   +1 more source

A Novel CoMAC-based cooperative spectrum sensing scheme in cognitive radio networks [PDF]

open access: yes, 2015
Conventional cooperative spectrum sensing (CSS) schemes in cognitive radio networks (CRNs) require that the secondary users (SUs) report their sensing data sequentially to the fusion center, which yields long reporting delay especially in the case of ...
Xu C(许驰)   +4 more
core  

Cooperative Spectrum Sensing over Non-Identical Nakagami Fading Channels [PDF]

open access: yes, 2011
Previous works in cooperative spectrum sensing assumed that the channels for sensing and reporting are independent identical distributed (i.i.d). A more practical and appropriate assumption, however, should be that the sensing channels and reporting ...
Anlei Rao   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Spectrum Sensing and Security Challenges and Solutions: Contemporary Affirmation of the Recent Literature [PDF]

open access: yes, 2014
Cognitive radio (CR) has been recently proposed as a promising technology to improve spectrum utilization by enabling secondary access to unused licensed bands. A prerequisite to this secondary access is having no interference to the primary system. This
Dr. Srihari   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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