Results 1 to 10 of about 1,560,074 (286)
SLAS Technology, 2023 Laboratory automation uses large amounts of plastic consumables, generating substantial single-use plastic waste. Automated ELISAs are an indispensable analytical tool in vaccine formulation and process development.
Brittney Pedrazzi +7 more
doaj +1 more source
A perspective on the discovery of enzyme activators
SLAS Discovery, 2022 Enzyme activation remains a largely under-represented and poorly exploited area of drug discovery despite some key literature examples of the successful application of enzyme activators by various mechanisms and their importance in a wide range of ...
Antonia Turberville +4 more
doaj +1 more source
EndoBind detects endogenous protein-protein interactions in real time
Communications Biology, 2021 Bill et al describe two high-throughput methods to detect protein-protein interactions in cells in real-time using the split-NanoLuciferase-complementation system.
Anke Bill +12 more
doaj +1 more source
Navigating the Landscape: A Comprehensive Review of Current Virus Databases
Viruses, 2023 Viruses are abundant and diverse entities that have important roles in public health, ecology, and agriculture. The identification and surveillance of viruses rely on an understanding of their genome organization, sequences, and replication strategy ...
Muriel Ritsch +3 more
doaj +1 more source
High throughput screening of 0.5 million compounds against CRAF using Alpha CETSAⓇ
SLAS Discovery, 2023 The cellular thermal shift assay (CETSA®) has increasingly been used in early drug discovery to provide a measure of cellular target engagement. Traditionally, CETSA has been employed for bespoke questions with small to medium throughput and has ...
Hannah Rowlands +9 more
doaj +1 more source
Decoding cell-type contributions to the cfRNA transcriptomic landscape of liver cancer
Human Genomics, 2023 Background Liquid biopsy, particularly cell-free RNA (cfRNA), has emerged as a promising non-invasive diagnostic tool for various diseases, including cancer, due to its accessibility and the wealth of information it provides.
Aram Safrastyan +2 more
doaj +1 more source
A Novel Approach To Identify Inhibitors of Iron Acquisition Systems of Pseudomonas aeruginosa
Microbiology Spectrum, 2022 Pseudomonas aeruginosa is an opportunistic pathogen that has been declared by the World Health Organization as a “priority 1 critical pathogen” needing immediate new strategies for chemotherapy. During infection, P.
Mamie Kannon +5 more
doaj +1 more source
Sensing-Throughput Tradeoff for Interweave Cognitive Radio System: A Deployment-Centric Viewpoint [PDF]
, 2015 Secondary access to the licensed spectrum is viable only if interference is avoided at the primary system. In this regard, different paradigms have been conceptualized in the existing literature.
Chatzinotas, Symeon +4 more
core +3 more sources
Decentralized Throughput Scheduling [PDF]
, 2013 Motivated by the organization of distributed service systems, we study models for throughput scheduling in a decentralized setting. In throughput scheduling, a set of jobs $j$ with values $w_j$, processing times $p_{ij}$ on machine $i$, release dates $r_j$ and deadlines $d_j$ , is to be processed non-preemptively on a set of unrelated machines.
de Jong, Jasper +2 more
openaire +3 more sources
Predicting expected TCP throughput using genetic algorithm [PDF]
, 2016 Predicting the expected throughput of TCP is important for several aspects such as e.g. determining handover criteria for future multihomed mobile nodes or determining the expected throughput of a given MPTCP subflow for load-balancing reasons.
Hernandez Benet, Cristian +2 more
core +2 more sources