Results 41 to 50 of about 1,018,067 (289)

Novel Antiretroviral Structures from Marine Organisms

open access: yesMolecules, 2019
In spite of significant advancements and success in antiretroviral therapies directed against HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form and become reactivated under favorable conditions.
Karlo Wittine   +3 more
doaj   +1 more source

High-throughput detection of metal contamination in HTS outputs

open access: yesSLAS Discovery, 2022
Large compound libraries utilised for HTS often include metal contaminated compounds which can interfere with assay signal or target biology, and therefore appear as hits.
Corinne Molyneux   +5 more
doaj   +1 more source

Throughput Analysis of General Network Coding Nodes Based on SW-ARQ Transmission [PDF]

open access: yes, 2010
The steady-state throughput of general network coding node is investigated, when data is transmitted in packets based on the stop-and-wait automatic repeat request (SW-ARQ) error-control scheme.
Yang, Lie-Liang, Qin, Yang
core   +2 more sources

Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation

open access: yesStem Cells International, 2016
Current approaches in human embryonic stem cell (hESC) to pancreatic beta cell differentiation have largely been based on knowledge gained from developmental studies of the epithelial pancreas, while the potential roles of other supporting tissue ...
Holger A. Russ   +8 more
doaj   +1 more source

Genomic analysis of 61 Chlamydia psittaci strains reveals extensive divergence associated with host preference

open access: yesBMC Genomics, 2023
Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse   +7 more
doaj   +1 more source

High Throughput Screens Yield Small Molecule Inhibitors of Leishmania CRK3:CYC6 Cyclin-Dependent Kinase [PDF]

open access: yes, 2011
Background: Leishmania species are parasitic protozoa that have a tightly controlled cell cycle, regulated by cyclin-dependent kinases (CDKs). Cdc2-related kinase 3 (CRK3), an essential CDK in Leishmania and functional orthologue of human CDK1, can form ...
Walker, Roderick G.   +9 more
core   +3 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo

open access: yesFrontiers in Pharmacology, 2018
Unique and outstanding physical and chemical properties of zeolite materials make them extremely useful in a variety of applications including agronomy, ecology, manufacturing, and industrial processes.
Sandra Kraljević Pavelić   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exploring the impact of primer length on efficient gene detection via high-throughput sequencing

open access: yesNature Communications
Reverse transcription (RT) is a crucial step in most RNA analysis methods. Optimizing protocols for this initial stage is critical for effective target detection, particularly when working with limited input RNA.
Julia Micheel   +3 more
doaj   +1 more source

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