Results 41 to 50 of about 1,052,538 (294)

Automation of biochemical assays using an open-sourced, inexpensive robotic liquid handler

open access: yesSLAS Technology
High Throughput Screening is crucial in pharmaceutical companies for efficient testing in drug discovery and development. Our Vaccines Analytical Research and Development (V-AR&D) department extensively uses robotic liquid handlers in their High ...
George Moukarzel   +6 more
doaj   +1 more source

Polyphenol-Based Design of Functional Olive Leaf Infusions

open access: yesFood Technology and Biotechnology, 2019
The beneficial properties of polyphenols are widely recognized, and polyphenol-rich olive oil, which is part of the typical Mediterranean diet, has been identified as having positive health effects.
Željka Peršurić   +3 more
doaj   +1 more source

Genomic analysis of 61 Chlamydia psittaci strains reveals extensive divergence associated with host preference

open access: yesBMC Genomics, 2023
Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse   +7 more
doaj   +1 more source

Approximations for Throughput Maximization

open access: yesAlgorithmica
In this paper we study the classical problem of throughput maximization. In this problem we have a collection $J$ of $n$ jobs, each having a release time $r_j$, deadline $d_j$, and processing time $p_j$. They have to be scheduled non-preemptively on $m$ identical parallel machines.
Hyatt-Denesik, Dylan   +2 more
openaire   +9 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo

open access: yesFrontiers in Pharmacology, 2018
Unique and outstanding physical and chemical properties of zeolite materials make them extremely useful in a variety of applications including agronomy, ecology, manufacturing, and industrial processes.
Sandra Kraljević Pavelić   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Development and Performance of High Chromium White Cast Irons (HCWCIs) for Wear–Corrosive Environments: A Critical Review

open access: yesMetals, 2023
There is a huge demand for high-performance materials in extreme environments involving wear and corrosion. High chromium white cast irons (HCWCIs) display better performance than many materials since they are of sufficient hardness for wear protection ...
Simbarashe Fashu, Vera Trabadelo
doaj   +1 more source

Increasing proteomics throughput [PDF]

open access: yesNature Biotechnology, 2021
A new dimension for analyzing mass spectrometry data allows rapid quantification of up to 70% more peptides.
openaire   +2 more sources

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