Results 51 to 60 of about 1,541,967 (286)

Development and Performance of High Chromium White Cast Irons (HCWCIs) for Wear–Corrosive Environments: A Critical Review

open access: yesMetals, 2023
There is a huge demand for high-performance materials in extreme environments involving wear and corrosion. High chromium white cast irons (HCWCIs) display better performance than many materials since they are of sufficient hardness for wear protection ...
Simbarashe Fashu, Vera Trabadelo
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Caching Gain in Wireless Networks with Fading: A Multi-User Diversity Perspective

open access: yes, 2013
We consider the effect of caching in wireless networks where fading is the dominant channel effect. First, we propose a one-hop transmission strategy for cache-enabled wireless networks, which is based on exploiting multi-user diversity gain.
Khalaj, Babak Hossein   +2 more
core   +1 more source

Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model

open access: yesCancer Cell International, 2022
Purpose Radiotherapy is one of the essential treatment modalities for nasopharyngeal carcinoma (NPC), however, radioresistance still poses challenges.
Yanhua Fang   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A General Class of Throughput Optimal Routing Policies in Multi-hop Wireless Networks

open access: yes, 2011
This paper considers the problem of throughput optimal routing/scheduling in a multi-hop constrained queueing network with random connectivity whose special case includes opportunistic multi-hop wireless networks and input-queued switch fabrics. The main
Javidi, Tara   +2 more
core   +1 more source

Meta-analysis of kindling-induced gene expression changes in the rat hippocampus

open access: yesFrontiers in Neuroscience, 2009
Numerous studies have been performed to examine gene expression patterns in the rodent hippocampus in the kindling model of epilepsy. However, recent reviews of this literature have revealed limited agreement among studies.
Sanja Rogic, Paul Pavlidis
doaj   +1 more source

Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

open access: yesCell Discovery, 2023
How cells adapt their gene expression to nutritional changes remains poorly understood. Histone H3T11 is phosphorylated by pyruvate kinase to repress gene transcription.
Xinyu Zhang   +7 more
doaj   +1 more source

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