Results 71 to 80 of about 901,459 (309)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

High-throughput technologies in polymer research Proceedings [PDF]

, 2002
High-Throughput Experimentation (HTE) is a well established technique in the pharmaceutical and biotechnology industries leading to faster and less expensive development of new drugs and therapies.
Gesellschaft fuer Chemische Technik und Biotechnologie e.V. (DECHEMA), Frankfurt am Main (Germany)
core  

Comparative Genome Analysis of 33 Chlamydia Strains Reveals Characteristic Features of Chlamydia Psittaci and Closely Related Species

Pathogens, 2020
To identify genome-based features characteristic of the avian and human pathogen Chlamydia (C.) psittaci and related chlamydiae, we analyzed whole-genome sequences of 33 strains belonging to 12 species. Using a novel genome analysis tool termed Roary ILP
Martin Hölzer, Lisa-Marie Barf, Kevin Lamkiewicz, Fabien Vorimore, Marie Lataretu, Alison Favaroni, Christiane Schnee, Karine Laroucau, Manja Marz, Konrad Sachse   +9 more
doaj   +1 more source

A critical review on development, performance and selection of stainless steels and nickel alloys for the wet phosphoric acid process

Materials & Design, 2023
The wet phosphoric acid (WPA) process equipment is exposed to corrosive and wear conditions with aggressiveness determined by the phosphate rock chemical composition and process parameters employed.
Simbarashe Fashu, Vera Trabadelo
doaj   +1 more source

Connectomics in high throughput [PDF]

Nature Methods, 2020
BRICseq provides access to brain-wide connectivity and can be combined with functional and transcriptomic studies for a comprehensive view of neuronal circuitry.
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

High-Throughput Analysis of the Plasma N-Glycome by UHPLC [PDF]

, 2016
The understanding of glycosylation alterations in health and disease has evolved significantly and glycans are considered to be relevant biomarker candidates.
O’Flaherty, R., Rudd, P. M., Henning Stöckmann, Pauline M. Rudd, Barbara Adamczyk, Karlsson, Niclas G.,, Stöckmann, H., Adamczyk, Barbara,, Niclas G. Karlsson, Róisín O’Flaherty   +9 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Throughput-efficient Lagrange coded private blockchain for secured IoT Systems [PDF]

, 2021
We develop a new Lagrange coded blockchain model for Internet-of-Things (IoT) systems based on Lagrange coded computing (LCC). In the model, a mining task assigned to a blockchain node (BN) is encoded with a specific encoding function.
Alia Asheralieva (17562462), Dusit Niyato (13395561)   +1 more
core  

RIBAP: a comprehensive bacterial core genome annotation pipeline for pangenome calculation beyond the species level

Genome Biology
Microbial pangenome analysis identifies present or absent genes in prokaryotic genomes. However, current tools are limited when analyzing species with higher sequence diversity or higher taxonomic orders such as genera or families.
Kevin Lamkiewicz, Lisa-Marie Barf, Konrad Sachse, Martin Hölzer   +3 more
doaj   +1 more source