Results 71 to 80 of about 60,064 (306)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Some Clues on the Conformational Stability of Globular Proteins
Trends in Peptide and Protein Sciences, 2019 The native structure of the glycine-rich antifreeze protein from snow flea, sfAFP, its conformational stability and cooperative folding-unfolding transitions represent a challenge for the current understanding and rationalization of protein folding and ...
Giuseppe Graziano
doaj +1 more source
The Neuroscientist, 2013 Cooperation is essential for the functioning of human societies. To better understand how cooperation both succeeds and fails, recent research in cognitive neuroscience has begun to explore novel paradigms to examine how cooperative mechanisms may be encoded in the brain.
M. Stallen, A. G. Sanfey
openaire +6 more sources
Theoretical investigation into the cooperativity effect and thermodynamic property of β-nitroguanidine∙C2F4∙H2O ternary complex [PDF]
, 2020 The H-bonding cooperativity effects in β-NQ (nitroguanidine)∙∙∙C2F4∙∙∙H2O ternary complex are investigated by the B3LYP and MP2(full) methods with the 6-311++G(2df,2p) basis set. The thermodynamic cooperativity effects are evaluated at 298.15 K.
Li, Bin +2 more
core +7 more sources
Cooperativity in Solid-State Squaramides
, 2016 Using a dipyridyl squaramide derivative as a model, we have shown that cooperativity in hydrogen-bonded catemers plays a crucial role in defining the solid-state synthon of disecondary squaramides, overriding the preferred association mode in ...
Rafel Prohens (1411240) +8 more
core +3 more sources
FEBS Open Bio, EarlyView.Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
COMPULSORY COOPERATION AND COINCIDENTAL COOPERATION
Journal of Positive Management, 2011 The aim of the article is to prove that companies cooperate not only because they wish to, but also because they are forced to do it. Moreover, It turns out that sometimes firms cooperate in strategic alliances with partners which were not selected, but appeared coincidentally.
openaire +5 more sources
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Why all MODY variants in transcription factor genes are dominantly inherited
Frontiers in GeneticsMaturity-onset diabetes of the young (MODY) is an autosomal dominant form of monogenic diabetes, frequently caused by heterozygous loss-of-function variants in transcription factor (TF) genes. Why are MODY variants in TF genes dominantly inherited?
Roman Zug, Roman Zug
doaj +1 more source