Results 81 to 90 of about 58,890 (308)
Some Clues on the Conformational Stability of Globular Proteins
Trends in Peptide and Protein Sciences, 2019 The native structure of the glycine-rich antifreeze protein from snow flea, sfAFP, its conformational stability and cooperative folding-unfolding transitions represent a challenge for the current understanding and rationalization of protein folding and ...
Giuseppe Graziano
doaj +1 more source
COMPULSORY COOPERATION AND COINCIDENTAL COOPERATION
Journal of Positive Management, 2011 The aim of the article is to prove that companies cooperate not only because they wish to, but also because they are forced to do it. Moreover, It turns out that sometimes firms cooperate in strategic alliances with partners which were not selected, but appeared coincidentally.
openaire +5 more sources
The Neuroscientist, 2013 Cooperation is essential for the functioning of human societies. To better understand how cooperation both succeeds and fails, recent research in cognitive neuroscience has begun to explore novel paradigms to examine how cooperative mechanisms may be encoded in the brain.
M. Stallen, A. G. Sanfey
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Games, 2018 To examine the stability of prosocial behavior in groups and pairs, we use an indirect approach. We conducted linear public good experiments with two and four subjects repeatedly three times at intervals of one week. All experiments were carried out without providing feedback and used a payment mechanism promoting stable behavior. We study the dynamics
Markus Sass +2 more
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Entrapment of hemocyanin conformers as a tool for the definition of the structural model of cooperativity [PDF]
, 2013 Allostery has been established as a fundamental mechanism of regulation in most biological processes (Changeux, 2012). The most studied allosteric protein is hemoglobin, that has long been considered a paradigm for the investigation of allostery and ...
Minute, Fabrizio
core
Origin of cooperativity in hydrogen bonding
, 2017 Hydrogen bond cooperativity results from interactions between effective point dipoles which account for many-body contributions to cooperativity.
Cristina Cuautli +2 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Role of fluctuations in ligand binding cooperativity of membrane receptors [PDF]
, 2011 Signal transduction upon binding of a ligand to a membrane protein can occur not only via allosteric conformational changes but also through fluctuations. We report a numerical study on the influence of conformational fluctuations on the cooperativity of
Peter G. Bolhuis +5 more
core +2 more sources
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Cooperativity length scale in nanocomposites: Interfacial and confinement effects [PDF]
, 2013 International audienceInterfacial and confinement effects on the evolution of cooperativity on approaching the glass transition have been studied in poly(propylenecoethylene) functionalized with diethylmaleate, polyethylene 1,4-cyclohexylenedimethylene ...
Couderc, H. +5 more
core +1 more source