Results 201 to 210 of about 110,836 (263)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Real-Time Lightweight Weld Seam Keypoint Detection and Tracking via an Improved SimCC with a Unified Three-Keypoint Formulation. [PDF]

Sensors (Basel)
Wang S, Huang X, Gao A, Chen C, Du F.
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Lesion topography shapes motor thresholds in brain tumor patients. [PDF]

Neuroimage Clin
Stark A, Goloshchapova K, Spolaore A, Gorbachuk M, Gkampenis A, Wang S, Machetanz K, Tatagiba M, Naros G.   +8 more
europepmc   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Identification of Novel Risk Loci for Common B-Cell Lymphoma Subtypes Through Cross-Trait Analysis with Idiopathic Inflammatory Myopathies. [PDF]

Cancers (Basel)
Che WI, Jarvis JN, International Lymphoma Epidemiology Consortium InterLymph, Imacs Genetics Group Myogen, Lundberg IE, Smedby KE, Lamb JA, Holmqvist M.   +7 more
europepmc   +1 more source

Altered cortical thickness in type 2 diabetes mellitus patients revealed by coordinate-based meta-analysis. [PDF]

BMC Endocr Disord
Han S, Li J, Zhang H, Ping L, Zhou C.
europepmc   +1 more source

Improving Astrometric Precision with MLP-Driven Super-Resolution of Star Maps. [PDF]

Sensors (Basel)
Lu Y, Xu X, Yan J, Zhang N, Lv Y.
europepmc   +1 more source

Comparative Performance Evaluation of Multi-Type LiDAR Sensors and Their Applicability to Sidewalk HD Mapping. [PDF]

Sensors (Basel)
Lee D, Kang S, Lee J, Kim J.
europepmc   +1 more source

Efficient acceleration of energetic electrons upstream of Earth's bow shock. [PDF]

Nat Commun
Liu YY, Song YT, Cao JB, Liu CM, Li SB, Russell CT, Pollock CJ, Lindqvist PA, Burch JL, Lu HY.   +9 more
europepmc   +1 more source