Results 81 to 90 of about 116,296 (308)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

A domain decomposition method for conformal mapping onto a rectangle

open access: yes, 1989
Let g be the function which maps conformally a simply-connected domain G onto a rectangle R so that four specified points z1, z2, z3, z4,o n ∂G are mapped respectively onto the four vertices of R.
Stylianopoulos, N S, Papamichael, N
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Hierarchical autoencoder enhanced chemistry coordinate mapping

open access: yes
We propose a machine learning-enhanced chemistry coordinate mapping (CCM) method that accelerates the integration of detailed chemical kinetics in reactive flow simulations by grouping chemically similar computational cells into clusters/zones within a ...
Yu, Rixin, Bai, Xue Song, Feng, Sheng
core   +1 more source

Navigation Map Construction Based on Semantic Segmentation and Multi-Submap Integration

open access: yesApplied Sciences
Traditional visual simultaneous localization and mapping (SLAM) systems typically generate sparse or semi-dense point cloud maps, which are insufficient for effective navigation and path planning.
Gang Li, Chen Huang, Jian Yu, Hao Luo
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Loss-of-function analysis of EphA receptors in retinotectal mapping [PDF]

open access: yes, 2004
Peer ...
Nakamoto, Masaru   +12 more
core   +1 more source

Bijective Mappings with Generalized Barycentric Coordinates: A Counterexample [PDF]

open access: yesJournal of Graphics Tools, 2013
Many recent works attempt to generalize barycentric coordinates to arbitrary polygons. I construct a counterexample proving that no such generalization will produce purely bijective mappings in the plane, provided the coordinates meet the Lagrange, reproduction, and partition of unity properties.
openaire   +1 more source

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