Results 31 to 40 of about 3,373,432 (240)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A New Method for Measuring Perforated Surface by Coordinate Measuring Machine (CMM) [PDF]
Nowadays CMM machines are widely used in surface measurement and inspection. As inspection results from CMM machine are obtained by the means of measuring surfaces with direct contact, they are more precise than non-contact method (like optical ...
MohammadMahdi Amiri
doaj
As a key part of the articulated arm coordinate measuring machine, the probe can determine the measurement accuracy. Therefore, the error source and influencing factors of the equivalent diameter of the probe are studied.
Zai Luo, Hui Liu, Dong Li, Kun Tian
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Supplemental Files: Laser Scanner-Based Robotic Coordinate Measuring Machine
This data represents the LabView and C++ software necessary to operate the coordinate measuring machine (CMM) described in the related publication, as well as raw data results representing the digitized model of a section of a turbine blade obtained ...
Gurau, Vladimir
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Performance of a five-axis machine tool as a coordinate measuring machine (CMM)
The use of machine tools for on-machine coordinate measurement on the workpiece is becoming commonplace. However, numerous errors can adversely affect the measurement accuracy. For instance, the inter-axis parameters are major contributors to the overall
Md Mizanur RAHMAN, Rene MAYER
doaj +1 more source
Multiple-sensor integration for efficient reverse engineering of geometry [PDF]
This paper describes a multi-sensor measuring system for reverse engineering applications. A sphere-plate artefact is developed for data unification of the hybrid system.
Longstaff, Andrew P. +3 more
core +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

