Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
R-Vivaldi:distance range-aware IP network coordinate system
Tongxin xuebao, 2012 The experience showed that the predicted delay's accuracy was improved when the nodes were chosen around the given delay as anchors.Thus a distance range-aware IP network coordinate system(R-Vivaldi) was proposed.The main idea was:according to the ...
Da-bin WANG +3 more
doaj +2 more sources
Generalized magnetostatic target field method for shielded magnetic field coils in a separable coordinate system. [PDF]
J Appl Phys, 2023 Lee SK, Schenck J.
europepmc +1 more source
Power System Recovery Coordinated with (Non-)Black-Start Generators [PDF]
, 2023 Meng Zhao +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Enhancing Fall Detection Accuracy: The Ground-Face Coordinate System for 3D Accelerometer Data
Sakarya University Journal of Computer and Information SciencesThe global elderly population is on the rise, leading to increased physical, sensory, and cognitive changes that heighten the risk of falls. Consequently, fall detection (FD) has emerged as a significant concern, attracting considerable attention in ...
Abdullah Talha Sözer
doaj +1 more source
Three-dimensional computed tomographic angular measurements of the canine tibia using a bone-centered coordinate system. [PDF]
Front Vet Sci, 2023 Brühschwein A +4 more
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
A new way of analyzing tooth movement using universal coordinate system geometry single point superposition in a 3D model. [PDF]
Dental Press J Orthod, 2023 Souza RXS +7 more
europepmc +1 more source