Results 61 to 70 of about 2,046,742 (302)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Coordinate systems, geodetic datums and coordinate transformation
This article makes an effort to define some types of coordinate systems and geodetic datums. Also it points out the importance of making connection between the local datum in which all state maps are prepared and the geocentric datum in which GPS works.
Branko Božić
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Geostationary Orbital Targets Imaging Based on Ground-Based Multiple-Input Multiple-Output Radar
Compared with the Earth’s surface, geostationary orbital (GEO) targets are relatively static, which makes it difficult to obtain two-dimensional radar images when the radar is ground-based without movement.
Lei Qiu +6 more
doaj +1 more source
Analysis of the form vault temple bearing by the laser apparatus LEICA TCR 305 [PDF]
As an object of mapping we choosed some of churches as an object of mapping. Ve determined the aisle of Rozalia church in Košice by means using the apparatus Leica TCR 305. The oblique transverse profile was measured.
Ľudovít Kovanič, jr. +2 more
doaj
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Review of Fast Back Projection Algorithms in Synthetic Aperture Radar
The Back Projection (BP) algorithm is an important direction in the development of synthetic aperture radar imaging algorithms. However, the large computational load of the BP algorithm has hindered its development in engineering applications. Therefore,
Mengdao XING +4 more
doaj +1 more source
Vzpostavitev ESRS v Sloveniji : Realization of ESRS in Slovenia [PDF]
The purpose of the paper is to present the introduction and implementation of the new state reference system in Slovenia. The new system will be a realization of the European reference system ESRS (European Spatial Reference System) in our territory ...
Bojan Stopar
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

