Results 111 to 120 of about 1,968,432 (294)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Известия высших учебных заведений России: РадиоэлектроникаIntroduction. In order to increase the accuracy of estimating the coordinates of a target, it is necessary to compensate for systematic errors in the nonlinear transformation of coordinates from a spherical system to a Cartesian one.
V. N. Burov +3 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Classification of human physical activity based on raw accelerometry data via spherical coordinate transformation. [PDF]
Stat Med, 2020 Kos M, Bogdan M, Glynn NW, Harezlak J.
europepmc +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Local Coordinate Transformation System With Non-sibsonian [PDF]
, 2009 Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2009Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2009Günümüzde harita üretimi ve kullanımında, koordinat ve konum bilgisinin doğru ve ...
Ceylan, Elif
core
Weighted coordinate transformation formulated by standard least-squares theory
, 2017 This paper presents a universal model of weighted coordinate transformation, i.e. transformation considering the errors of coordinates in both coordinate systems. It is intrinsically one of the typical examples of 'error-in-variables' (EIV) models.
Ž. Cvijetinović +3 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Using reinforcement learning to coordinate better
, 2005 This paper examines the potential and the impact of introducing learning capabilities into autonomous agents that make decisions at run-time about which mechanism to exploit in order to coordinate their activities. Specifically, our motivating hypothesis
Jennings, N. R. +5 more
core +2 more sources