Results 51 to 60 of about 123,790 (304)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

2-DOF Angle Measurement of Rocket Nozzle with Multivision

Advances in Mechanical Engineering, 2013
A real-time measurement method is presented for the 2-DOF swing angles of rocket nozzle by the use of multivision and rocket nozzle rotation axes.
Yubo Guo, Gang Chen, Dong Ye, Xiaoyu Yu, Feng Yuan   +4 more
doaj   +1 more source

Impacts of North Carolina’s medicaid transformation on community transit systems: A qualitative analysis with policy implications

Transportation Research Interdisciplinary Perspectives, 2023
North Carolina began its Medicaid Transformation implementation process in July of 2021. The Transformation shifted responsibility for arranging non-emergency medical transportation (NEMT) for transportation-disadvantaged Medicaid beneficiaries from ...
Manuel Santana Palacios, Noreen McDonald, Evan Iacobucci   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Detail Explanation of Coordinate Transformation Procedures Used in Geodesy and Geoinformatics on the Example of the Territory of the Republic of Croatia

Applied Sciences
With strong technology improvement, especially GNSS, coordinate transformation has become an essential tool in everyday practice. For this reason, it is beneficial to have a good understanding of the mathematical process of coordinate transformation, as ...
Tedi Banković, Marin Dubrović, Antonio Banko, Marko Pavasović   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

An optimized hexagonal quadtree encoding and operation scheme for icosahedral hexagonal discrete global grid systems

International Journal of Digital Earth, 2022
Although research on the discrete global grid systems (DGGSs) has become an essential issue in the era of big earth data, there is still a gap between the efficiency of current encoding and operation schemes for hexagonal DGGSs and the needs of practical
Long Zhao, Guoqing Li, Xiaochuang Yao, Yue Ma, Qianqian Cao   +4 more
doaj   +1 more source

3D coordinate transformation using molodensky badekas transformation model: MBT07 [PDF]

, 2007
Transformations between coordinate systems are routinely carried out in surveying. As satellite positioning techniques are more frequently used, transformations of three-dimensional (3D) coordinates will become a common practice.
Phang, Seng Boon, Setan, Halim
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source