Results 71 to 80 of about 1,968,432 (294)

Cylindrical superlens by a coordinate transformation [PDF]

open access: yesPhysical Review B, 2008
Minor changes to conform with the published ...
Yan, Min, Yan, Wei, Qiu, Min
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Designs for thermal harvesting with nonlinear coordinate transformation

open access: yesAIP Advances, 2018
In this paper a thermal concentrating design method was proposed based on the concept of generating function without knowing the needed coordinate transformation beforehand.
Qingxiang Ji, Guodong Fang, Jun Liang
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

An optimized hexagonal quadtree encoding and operation scheme for icosahedral hexagonal discrete global grid systems

open access: yesInternational Journal of Digital Earth, 2022
Although research on the discrete global grid systems (DGGSs) has become an essential issue in the era of big earth data, there is still a gap between the efficiency of current encoding and operation schemes for hexagonal DGGSs and the needs of practical
Long Zhao   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Least squares support vector machine model for coordinate transformation

open access: yesGeodesy and Cartography, 2019
In coordinate transformation, the main purpose is to provide a mathematical relationship between coordinates related to different geodetic reference frames. This gives the geospatial professionals the opportunity to link different datums together. Review
Yao Yevenyo Ziggah   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Coordinate system connected with lower extremity and its application to knee impulsive force induced by landing after vertical fall [PDF]

open access: yes, 2006
New coordinate system connected with the lower extremity is contrived and the transformation rule to such a coordinate system from any Cartesian coordinate system is derived.
畠中, 泰彦   +11 more
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