Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition. Dysbiosis is commonly observed. This study identified distinct sinonasal microbial communities in CRSwNP patients and explored their clinical and pathological associations. Two distinct microbial communities were identified: community type 1 (CT1), dominated by
Bixing Fang +10 more
wiley +1 more source
The Role of Vitamin D in Chronic Obstructive Pulmonary Disease: Mechanisms and Clinical Implications. [PDF]
Aggarwal K +5 more
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Mechanical Forces and Mechanotransduction in COPD: Pathogenesis, Clinical Phenotypes, and Therapeutic Implications. [PDF]
Li J +7 more
europepmc +1 more source
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li +3 more
wiley +1 more source
Effect of Incentive Spirometry Exercise on Perceived Stress in Chronic Obstructive Pulmonary Disease Patients: A Quasi-Experimental Study. [PDF]
Rajpoot NN +6 more
europepmc +1 more source
Visual Patterns of Diaphragmatic Motion in Acute Respiratory Failure: A Prospective Pilot Study
In this prospective bicentric study, we studied the relationship between the appearance of diaphragmatic motion and the etiological diagnosis of patients admitted to the emergency department with ARF. We observed a different visual pattern in patients with pneumonia. This is an interesting result as it allows the diagnosis of pneumonia without the need
Thibaut Markarian +7 more
wiley +1 more source
Inflammation Levels and the Health Impact of Anti-Inflammatory Diets on Chronic Obstructive Pulmonary Disease: An NHANES Study. [PDF]
Feng T, Yu W.
europepmc +1 more source
Abstract Background Sex differences in the clinical presentation of autism are established, but evidence on early‐life co‐occurring physical illnesses in early‐diagnosed autistic individuals is scarce. This nationwide cohort study examined sex‐stratified incidence of physical illnesses within 5 years after autism spectrum disorder (ASD) diagnosis in ...
Yu‐Chieh Chuang +6 more
wiley +1 more source
Blood eosinophil count as a biomarker for therapy guidance in COPD and asthma exacerbations. [PDF]
Godallage AN +5 more
europepmc +1 more source

