Results 61 to 70 of about 629,305 (401)

The unmet global burden of COPD

Global Health, Epidemiology and Genomics, 2018
Chronic respiratory diseases receive little attention and funding in comparison with other major causes of global morbidity and mortality [1]. Chronic obstructive pulmonary disease (COPD) is a major public health problem.
Shumonta Quaderi, J. Hurst
semanticscholar   +1 more source

Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker, Bryant R. England, Michael D. George, Hannah Brubeck, Brian Sauer, Aleksander Lenert, Punyasha Roul, Geoffrey M. Thiele, Ted R. Mikuls, Katherine D. Wysham   +9 more
wiley   +1 more source

Validation of new predictors of mortality and BODE index variants in patients with COPD at moderate altitude

ERJ Open Research
Background COPD ranks as the third leading global cause of mortality. Despite the widespread use of the BODE index and its variants for mortality prediction, their accuracy may be affected by factors like ethnicity, altitude and regional disparities ...
Robinson Robles-Hernández, Gustavo I. Centeno-Saenz, Alejandra Ramírez-Venegas, Ireri Thirion-Romero, Rafael Hernández-Zenteno, Sandra P. Guinto-Ramírez, María C. Maya-García, Diana Villegas-Trejo, Francisco Montiel-López, Lila M. Cordero-Silis, Rogelio Pérez-Padilla   +10 more
doaj   +1 more source

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers

Respiratory Research, 2019
Cigarette smoking is one of the major risk factors for the development of chronic obstructive pulmonary disease (COPD). Evidence is accumulating that Receptor for Advanced Glycation-End products (RAGE)-signaling is a key pathway in the pathophysiology of
Alen Faiz, Maarten van den Berge, Cornelis J. Vermeulen, Nick H. T. ten Hacken, Victor Guryev, Simon D. Pouwels   +5 more
doaj   +1 more source

Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study. [PDF]

, 2015
BACKGROUND: Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic ...
A Hardwell, AH Boer de, AR Clark, BL Laube, Dinesh Saralaya, EF Juniper, F Lavorini, GM Hawksworth, H Chrystyn, H Chrystyn, H Chrystyn, H Chrystyn, Harold Hosker, Henry Chrystyn, JL Rau, JP Koning de, KR Chapman, L Bentur, ME Broeders, ME Broeders, MH Dewar, ML Everard, PH Brown, Philip Chetcuti, RA Al-Showair, V Giraud, W Azouz, W Azouz, Wahida Azouz, WE Kamin, WM Nsour   +30 more
core   +1 more source

European Respiratory Society guidelines on long-term home non-invasive ventilation for management of COPD

European Respiratory Journal, 2019
Background While the role of acute non-invasive ventilation (NIV) has been shown to improve outcome in acute life-threatening hypercapnic respiratory failure in COPD, the evidence of clinical efficacy of long-term home NIV (LTH-NIV) for management of ...
B. Ergan, S. Oczkowski, B. Rochwerg, A. Carlucci, M. Chatwin, E. Clini, M. Elliott, J. Gonzalez-Bermejo, N. Hart, M. Luján, J. Nasiłowski, S. Nava, J. Pépin, L. Pisani, J. Storre, P. Wijkstra, T. Tonia, Jeanette Boyd, R. Scala, W. Windisch   +19 more
semanticscholar   +1 more source

The COPD Pipeline

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2009
Smoking Cessation. Nabi Biopharmaceuticals has received a NIDA grant of $4+ million in partial support of the next and, one hopes, final phases of a possible nicotine conjugate vaccine.
openaire   +3 more sources

Clinical Outcomes Of Patients Within The Rheumatoid Arthritis Care Pathway Cohort At a Tertiary Care Integrated Delivery Network: A Comparison To Usual Care

Arthritis Care &Research, Accepted Article.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multi‐disciplinary team‐based care. Clinical and insurance claims data were extracted to compare
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep [PDF]

, 2006
Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large- animal model of emphysema using repeated LPS administration into sheep lung segments. An
Baker, Alison, Blundell, Richard, Collie, D David S, McLean, Nicola, Milne, Elspeth, Rhind, Susan, Sallenave, Jean-Michel, Woodall, Chris   +7 more
core   +2 more sources

Defining the relationship between COPD and CVD: what are the implications for clinical practice?

Therapeutic Advances in Respiratory Disease, 2018
Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic obstructive pulmonary disease (COPD). CVDs are common in people with COPD, and their presence is associated with increased risk for hospitalization, longer length of ...
A. Morgan, R. Zakeri, J. Quint
semanticscholar   +1 more source