Results 71 to 80 of about 602,916 (384)

Defining the relationship between COPD and CVD: what are the implications for clinical practice?

Therapeutic Advances in Respiratory Disease, 2018
Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic obstructive pulmonary disease (COPD). CVDs are common in people with COPD, and their presence is associated with increased risk for hospitalization, longer length of ...
A. Morgan, R. Zakeri, J. Quint
semanticscholar   +1 more source

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

Advanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao, Hui Zhang, Jingyi Wu, Yaqi Huang, Xiangnan Li, Meijia Wang, Shuming Wang, Jiaofeng Wang, Jie Chen, Zhi jun Bao, Li Jin, Xiaofeng Wang, Zixin Hu, Shuai Jiang, Yi Li   +14 more
wiley   +1 more source

National clinical audit for hospitalised exacerbations of COPD

ERJ Open Research, 2020
Introduction Exacerbations of COPD requiring hospital admission are burdensome to patients and health services. Audit enables benchmarking performance between units and against national standards, and supports quality improvement.
John R. Hurst, Jennifer K. Quint, Robert A. Stone, Yvonne Silove, Jane Youde, C. Michael Roberts   +5 more
doaj   +1 more source

FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in single-cell RNA-sequencing datasets

BMC Genomics, 2023
Cell type-specific differential gene expression analyses based on single-cell transcriptome datasets are sensitive to the presence of cell-free mRNA in the droplets containing single cells.
Marijn Berg, Ilya Petoukhov, Inge van den Ende, Kerstin B. Meyer, Victor Guryev, Judith M. Vonk, Orestes Carpaij, Martin Banchero, Rudi W. Hendriks, Maarten van den Berge, Martijn C. Nawijn   +10 more
doaj   +1 more source

Eosinophil and T Cell Markers Predict Functional Decline in COPD Patients [PDF]

, 2009
BACKGROUND. The major marker utilized to monitor COPD patients is forced expiratory volume in one second (FEV1). However, asingle measurement of FEV1 cannot reliably predict subsequent decline.
A Papi, AK Sullivan, AT Society, B Barcelo, B Meshi, BH Nelson, C Fletcher, CS Robbins, CS Robbins, DL Mueller, DW Perng, F Mor, G Rohde, GJ de Bree, J Chang, J Chang, JL Hankinson, L Lintomen, L Taraseviciene-Stewart, L Van Parijs, L Van Parijs, M Decramer, M Miller, M Saetta, M Saetta, MD Roth, N Tzanakis, NR Anthonisen, P Glader, PC Doherty, PD Ponath, PD Ponath, PJ Barnes, PT King, RO Crapo, RW Vandivier, S Chakrabarti, S Hodge, S Hodge, S Hodge, S Wei, T Seemungal, TC O'Shaughnessy, V Bocchino   +43 more
core   +4 more sources

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.

New England Journal of Medicine, 2019
BACKGROUND Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD). METHODS We performed a multicenter,
C. Butler, D. Gillespie, P. White, Janine Bates, Rachel Lowe, E. Thomas-Jones, M. Wootton, K. Hood, Rhiannon Phillips, H. Melbye, C. Llor, J. Cals, G. Naik, N. Kirby, M. Gal, Evgenia Riga, N. Francis   +16 more
semanticscholar   +1 more source

Imaging and COPD [PDF]

Jornal Brasileiro de Pneumologia, 2015
1. Laboratorio de Pesquisa em Imagens Medicas, Pavilhao Pereira Filho, Santa Casa de Misericordia de Porto Alegre, Porto Alegre (RS) Brasil. 2. Pontificia Universidade Catolica de Porto Alegre, Porto Alegre (RS) Brasil. COPD involves destruction of alveolar septa in the lungs, associated with small airway dilation that is partially irreversible.(1) The
openaire   +6 more sources

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

Advanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang, Xiangqin Ou, Jingyi Lin, Xiaofei Luo, Jiashun Zhou, Xingyue Zhou, Peihua Zhao, Li Liu, Ziran Zhao, Ying Zhou, Guanwei Fan, Lifeng Han, Xiumei Gao   +12 more
wiley   +1 more source

Reducing Agents Decrease the Oxidative Burst and Improve Clinical Outcomes in COPD Patients: A Randomised Controlled Trial on the Effects of Sulphurous Thermal Water Inhalation

The Scientific World Journal, 2013
Background. Inhalation of thermal water with antioxidant properties is empirically used for COPD. Aims. To evaluate the effects of sulphurous thermal water (reducing agents) on airway oxidant stress and clinical outcomes in COPD. Methods.
Marco Contoli, Giulia Gnesini, Giacomo Forini, Brunilda Marku, Alessia Pauletti, Anna Padovani, Paolo Casolari, Liliana Taurino, Andrea Ferraro, Milva Chicca, Adalberto Ciaccia, Alberto Papi, Silvano Pinamonti   +12 more
doaj   +1 more source

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu, Han Li, Shuang‐feng Zi, Ying Tang, Na Liu, Ke‐xin Li, Shi‐ke Geng, Hui‐qing Lu, Zhi‐kang Xie, Xin‐yi Xu, Yi‐ting Wei, Li‐xin Wang, Tao Liu, Jie Chao, Yi Yang, Hai‐bo Qiu, Wei Huang, Ling Liu   +17 more
wiley   +1 more source