Results 71 to 80 of about 404,062 (356)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

open access: yesNature Communications, 2018
Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia.
Aran Singanayagam   +28 more
doaj   +1 more source

Sarcopenia in COPD: a systematic review and meta-analysis

open access: yesEuropean Respiratory Review, 2019
COPD is associated with a progressive loss of muscle mass and function. However, there is an unmet need to define and standardise methods to estimate the prevalence of sarcopenia in COPD patients. We performed a systematic review and meta-analysis of the
E. Benz   +10 more
semanticscholar   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

Work absence in patients with asthma and/or COPD: a population-based study

open access: yesnpj Primary Care Respiratory Medicine, 2021
Chronic obstructive pulmonary disease (COPD) and asthma impact on work productivity, but their population-based burden and clinical predictors are understudied.
Boudewijn J. H. Dierick   +8 more
doaj   +1 more source

Under- and over-diagnosis of COPD: a global perspective

open access: yesBreathe, 2019
Globally, chronic obstructive pulmonary disease (COPD) is the fourth major cause of mortality and morbidity and projected to rise to third within a decade as our efforts to prevent, identify, diagnose and treat patients at a global population level have ...
T. Ho   +4 more
semanticscholar   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan   +12 more
wiley   +1 more source

The Fractional exhaled Nitric Oxide (FeNO)- test as add-on test in the diagnostic work-up of asthma: a study protocol

open access: yesBMC Pulmonary Medicine
Background Asthma is a common disease characterized by chronic inflammation of the lower airways, bronchial hyperactivity, and (reversible) airway obstruction. The Global Initiative of Asthma Guideline recommends a flowchart to diagnose asthma with first-
T. (Tuba) Kaya   +4 more
doaj   +1 more source

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

open access: yesAdvanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji   +12 more
wiley   +1 more source

Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations

open access: yesThorax, 2018
Background Alterations in the composition of the lung microbiome associated with adverse clinical outcomes, known as dysbiosis, have been implicated with disease severity and exacerbations in COPD.
D. Mayhew   +20 more
semanticscholar   +1 more source

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