Results 41 to 50 of about 4,950 (174)

Copeptin Hormone Concentrations in Dogs with Heart Disease and Relationship with Antidiuretic Hormone

Animals
Antidiuretic hormone (ADH) is upregulated in dogs with cardiac disease. However, measurement of ADH is impractical in a clinical setting. Copeptin is co-secreted with ADH, making it a potential biomarker of ADH secretion.
Corine Lavigne, Darcy B. Adin, Courtney Hanner, Alexis Cooper, Rebeca A. Castro, Autumn N. Harris   +5 more
doaj   +1 more source

Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study

Respiratory Research, 2017
Background Copeptin is a novel biomarker that predicts mortality in lower respiratory tract infections and heart failure (HF), but the diagnostic value of copeptin in acute dyspnea and the prognostic significance of copeptin in acute exacerbation of ...
Jacob A. Winther, Jon Brynildsen, Arne Didrik Høiseth, Heidi Strand, Ivar Følling, Geir Christensen, Ståle Nygård, Helge Røsjø, Torbjørn Omland   +8 more
doaj   +1 more source

Copeptin Implementation on Stroke Prognosis

, 2023
Predicting functional outcome following stroke is considered to be of key importance in an attempt to optimize overall stroke care. Although clinical prognostic tools have been widely implemented, optimal blood biomarkers might be able to yield ...
Nikolaos Aggelousis, Anastasia Sousanidou, Pinelopi Vlotinou, Antonia Kaltsatou, Foteini Christidi, Stella Karatzetzou, Dimitrios Tsiptsios, Eleftherios Stefas, Christos Kokkotis, Aimilios Gkantzios, Konstantinos Vadikolias, Styliani Fotiadou   +11 more
core   +1 more source

Seven days of mixed‐method heat acclimation improved markers of cardiovascular and fluid‐regulatory strain during exercise‐heat stress

Experimental Physiology, EarlyView.
Abstract A mixed‐method heat acclimation (HA) protocol may optimise performance by supporting the training taper while promoting thermal adaptation; however, the impact on cardiovascular and fluid‐regulatory adjustments to protect health is unknown. Therefore, we examined the effects of a mixed‐method heat protocol on physiological responses, including
Daniel Snape, Barney Wainwright, Iain T. Parsons, Michael J. Stacey, David R. Woods, John O'Hara   +5 more
wiley   +1 more source

Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5

BMC Nephrology, 2020
Background Vascular calcification (VC) is an independent predictor of cardiovascular disease (CVD) present in 30–70% of patients with chronic kidney disease (CKD).
Edyta Golembiewska, Abdul Rashid Qureshi, Lu Dai, Bengt Lindholm, Olof Heimbürger, Magnus Söderberg, Torkel B. Brismar, Jonaz Ripsweden, Peter Barany, Richard J. Johnson, Peter Stenvinkel   +10 more
doaj   +1 more source

Investigation of possible underlying mechanisms behind water-induced glucose reduction in adults with high copeptin

Scientific Reports, 2021
Elevated copeptin, a surrogate marker of vasopressin, is linked to low water intake and increased diabetes risk. Water supplementation in habitual low-drinkers with high copeptin significantly lowers both fasting plasma (fp) copeptin and glucose.
Sofia Enhörning, Tiphaine Vanhaecke, Alberto Dolci, Erica T. Perrier, Olle Melander   +4 more
doaj   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

Genetic Insights Into AVP Deficiency: Identification of a Novel AVP Variant and Compilation of a Curated Catalogue of Pathogenic Variants

Clinical Genetics, Volume 110, Issue 2, Page 203-209, August 2026.
We identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Jennifa Joseph, Esben Søndergaard, Sine Knorr, Jane Hagelskjær Knudsen, Søren Rittig, Jane Hvarregaard Christensen   +5 more
wiley   +1 more source

Impact of recurrent dehydration with mild periodic water restriction on blood pressure and renal function in male spontaneously hypertensive rats

Experimental Physiology, Volume 111, Issue 7, Page 3398-3411, 1 July 2026.
Abstract The kidneys regulate fluid balance but are susceptible to adverse effects of inadequate hydration. Epidemiological studies have linked low water intake to renal dysfunction and chronic kidney disease. Previously we showed that restricting water intake to a single 2‐h period daily for 4 weeks promotes hypertension as well as renal inflammation,
Katrina M. Mirabito Colafella, Peter N. H. Nguyen, Zoe McArdle, Debra Fong, Edmund Kwok, Kate M. Denton, Antony Vinh, Lucinda M. Hilliard Krause   +7 more
wiley   +1 more source

The stress hormone copeptin: a new prognostic biomarker in acute illness

Swiss Medical Weekly, 2010
Stress is defined as anything that throws the body out of homeostatic balance; for example an acute illness. Any stressor which activates the hypothalamo-pituitary-adrenal (HPA) axis leads to an increase in concentrations of the adrenal stress hormone,
M Christ-Crain
doaj   +1 more source