Results 21 to 30 of about 5,906 (213)
Serum Copeptin Rises After Tolvaptan for Hyponatraemia, but Does Not Predict Risk of Rapid Sodium Rise: Pre-Specified Secondary Analysis of the TVFR Trial. [PDF]
Clin Endocrinol (Oxf)ABSTRACT Objective Hyponatraemia is a common electrolyte disorder often driven by excess arginine vasopressin (AVP). Copeptin is a stable surrogate marker co‐secreted with AVP. It is unclear whether treatment of hyponatraemia with tolvaptan, an AVP‐V2 receptor antagonist, impacts copeptin.
Warren AM +4 more
europepmc +2 more sources
Copeptin is associated with the severity of endometriosis
Archives of Gynecology and Obstetrics, 2014 Endometriosis is defined as the presence of endometrial glands and stroma in ectopic locations and may be associated with local and systemic inflammatory processes. Copeptin is elevated in acute and chronic inflammation conditions. The aim of the present study was to determine whether serum copeptin levels were altered in women with endometriosis and ...
Abdullah, Tuten +7 more
openaire +3 more sources
Endocrines, 2021 Vasopressin (AVP) and copeptin are released in equimolar amounts from the same precursor. Due to its molecular stability and countless advantages as compared with AVP, copeptin perfectly mirrors AVP presence and has progressively emerged as a reliable marker of vasopressinergic activation in response to osmotic and hemodynamic stimuli in clinical ...
Martino, Marianna, Arnaldi, Giorgio
openaire +3 more sources
Clinical Biochemist Reviews, 2021 Direct measurement of the nonapeptide vasopressin has been limited by analyte instability ex vivo and in vivo rapid degradation, low serum concentrations requiring a sensitive assay and inherent secretory pulsatility. Copeptin is a 39 amino acid glycopeptide cleavage product of vasopressin synthesis with high stability, providing a marker of ...
R, Jalleh, D J, Torpy
openaire +2 more sources
Genetic Insights Into AVP Deficiency: Identification of a Novel AVP Variant and Compilation of a Curated Catalogue of Pathogenic Variants. [PDF]
Clin GenetWe identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Joseph J +5 more
europepmc +2 more sources
Angiology, 2016 Unic-Stojanovic et al, in this issue of Angiology, evaluated whether or not copeptin levels are associated with carotid cross-clamping in patients undergoing carotid endarterectomy (CEA). Although copeptin levels increased from baseline to postoperatively in all patients, no association was found between serum copeptin levels and the duration of ...
Kosmas I. Paraskevas +2 more
openaire +1 more source
The association of copeptin with metabolic risk markers is modified by region of origin
Scientific Reports, 2023 Iraqi born immigrants in Sweden have higher prevalence of metabolic diseases compared to native Swedes. Copeptin, a marker for vasopressin, is associated with increased risk of metabolic disease.
Anna Franzén +4 more
doaj +1 more source
Serum copeptin and copeptin/NT-proBNP ratio — new tools to differentiate takotsubo syndrome from acute myocardial infarction [PDF]
, 2020 Background: Today no established biomarkers are available for the early diagnosis of takotsubo syndrome and its differentiation from ST-segment elevation myocardial infarction.
Kucharz, Jakub +7 more
core +1 more source
Association between Copeptin and Metabolic Syndrome: A Systematic Review
Journal of Nutrition and Metabolism, 2022 Background. Copeptin, a reliable marker for vasopressin release, has been associated with cardiometabolic diseases including metabolic syndrome (MetS). This systematic review aims to evaluate the association between copeptin and MetS. Methods.
Ricardo Rojas-Humpire +3 more
doaj +1 more source
Frontiers in Endocrinology, 2022 ObjectiveThis study aimed to investigate the complex interactions of thyroid hormone, apelin, and copeptin in the fluid–ion homeostasis of patients with severe transitory hypothyroidism.MethodsIn this prospective observational study, 39 patients (ECOG: 0;
Marin Gergics +11 more
doaj +1 more source