Results 141 to 150 of about 8,729 (179)
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Seminars in Cell and Developmental Biology, 2007
Transport through the secretory pathway begins with COPII regulation of ER export. Driven by the Sar1 GTPase cycle, cytosolic COPII proteins exchange on and off the membrane at specific sites on the ER to regulate cargo exit. Here recent developments in COPII research are discussed, particularly the use of live-cell imaging, which has revealed ...
Theresa H Ward
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Transport through the secretory pathway begins with COPII regulation of ER export. Driven by the Sar1 GTPase cycle, cytosolic COPII proteins exchange on and off the membrane at specific sites on the ER to regulate cargo exit. Here recent developments in COPII research are discussed, particularly the use of live-cell imaging, which has revealed ...
Theresa H Ward
exaly +3 more sources
Role of Rab1b in COPII dynamics and function
European Journal of Cell Biology, 2011 In eukaryotic cells, proteins destined for secretion are translocated into the endoplasmic reticulum (ER) and packaged into so-called COPII-coated vesicles. In the ER exit sites (ERES), COPII has the capacity of deforming the lipid bilayer, where it modulates the selective sorting and concentration of cargo proteins.
Cecilia Alvarez, Pablo Monetta
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Lysophospholipids Facilitate COPII Vesicle Formation [PDF]
Current Biology, 2018 Coat protein complex II (COPII) proteins form vesicles from the endoplasmic reticulum to export cargo molecules to the Golgi apparatus. Among the many proteins involved in this process, Sec12 is a key regulator, functioning as the guanosine diphosphate (GDP) exchange factor for Sar1p, the small guanosine triphosphatase (GTPase) that initiates COPII ...
Kouichi Funato +2 more
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COPII-mediated traffic in plants
Trends in Plant Science, 2010The secretory pathway encloses functionally interlinked organelles for the synthesis and deposition of most of the building blocks of eukaryotic cells, such as lipids, proteins and sugars. The coat protein complex II (COPII) is a specialized protein complex for the transport between secretory organelles, specifically from the endoplasmic reticulum (ER)
MARTI, LUCIA +4 more
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A unique COPII population in plant autophagy
Autophagy, 2021Increasing evidence supports the bona fide function of the coat protein complex II (COPII) machinery in regulating autophagosomes biogenesis during macroautophagy/autophagy induced by nutrient starvation. However, the participation of the COPII machinery in the plant autophagy pathway remains elusive. We recently identified a unique population of COPII
Yonglun, Zeng, Liwen, Jiang
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Multifaceted roles of COPII subunits in autophagy
Biochimica Et Biophysica Acta - Molecular Cell Research, 2020 COPII vesicles mediate anterograde ER-Golgi traffic of newly synthesized proteins in nutrient rich conditions. An accumulating body of results indicates that the secretory COPII vesicles can be shifted to the roles in autophagosome formation and selective ER-phagy (autophagy of ER), depending on their specific subunits, in response to environmental ...
Zhongyu, Li, Wei, Huang, Wei, Wang
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Molecular mechanisms of COPII vesicle formation
Seminars in Cell & Developmental Biology, 2007The first step in protein secretion from eukaryotic cells is mediated by COPII vesicles, known for the cytoplasmic coat proteins that are the minimal machinery required to generate these small transport carriers. The five COPII coat components coordinate to create a vesicle by locally generating membrane curvature and populating the incipient bud with ...
Lee, Marcus C.S., Miller, Elizabeth A.
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COPII-mediated vesicle formation at a glance
Journal of Cell Science, 2011Eukaryotic cells contain a number of different membrane compartments that have specialized roles. Each compartment depends on a specific mixture of proteins for its identity and function. For many compartments, proteins arrive by way of small membrane vesicles that travel through the cell from ...
Devon, Jensen, Randy, Schekman
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1999
Abstract Genes encoding COPII proteins were first identified inS. cerevisiae through a genetic screen for secretion defective cells and later found to be required for transport vesicle budding from the ER. Subsequent biochemical approaches allowed for the isolation of three protein fractions, Sec23p/Sec24p complex, Sec13p/Sec31p, and ...
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Abstract Genes encoding COPII proteins were first identified inS. cerevisiae through a genetic screen for secretion defective cells and later found to be required for transport vesicle budding from the ER. Subsequent biochemical approaches allowed for the isolation of three protein fractions, Sec23p/Sec24p complex, Sec13p/Sec31p, and ...
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MODIFICATION TO COPII FOR 12XX
1962Abstract : Lockheed Missiles and Space Corporation (LMSC) has the integration responsibility for the 12XX flight series. When System Development Corporation becomes responsible for the 12XX series, it will be converted to the COPII (Control for Operational Programs) System. Outlines features in the 12XX COP that must be integrated into the COPII System.
J. B. Munson, Billie Rhae Pruett
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