Results 151 to 160 of about 8,702 (177)
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MODIFICATION TO COPII FOR 12XX
1962Abstract : Lockheed Missiles and Space Corporation (LMSC) has the integration responsibility for the 12XX flight series. When System Development Corporation becomes responsible for the 12XX series, it will be converted to the COPII (Control for Operational Programs) System. Outlines features in the 12XX COP that must be integrated into the COPII System.
J. B. Munson, Billie Rhae Pruett
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COPII and the regulation of protein sorting in mammals
Nature Cell Biology, 2011Secretory proteins are transported to the Golgi complex in vesicles that bud from the endoplasmic reticulum. The cytoplasmic coat protein complex II (COPII) is responsible for cargo sorting and vesicle morphogenesis. COPII was first described in Saccharomyces cerevisiae, but its basic function is conserved throughout all eukaryotes.
Giulia, Zanetti +4 more
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The COPII cage sharpens its image
Nature Structural & Molecular Biology, 2013Self-assembly of the COPII coat proteins Sec13 and Sec31 creates a spherical cage that drives vesicle formation from the endoplasmic reticulum. A multipronged approach now provides a convincing pseudoatomic model of the assembled cage that sharpens our understanding of the architecture, contact sites and flexibility of this remarkable structure.
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p38 MAPK regulates COPII recruitment
Biochemical and Biophysical Research Communications, 2007Here, we investigate regulation of coat protein complex II (COPII) recruitment onto ER export sites in permeabilized cells. In cytosols from nocodazole treated HeLa cells we find COPII loading is inhibited. The stress kinase p38 MAPK is activated in these cytosols and COPII loading can be rescued by depletion of p38 MAPK alpha or by the p38 MAPK ...
Wang, Lijun, Lucocq, John M.
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Illuminating COPII coat dynamics
Nature Structural & Molecular Biology, 2005A FRET-based approach to monitor the assembly of membrane-associated COPII coat proteins provides new insights into how the COPII–cargo complex is maintained on the membrane during continuous rounds of Sar1p-GTP hydrolysis.
Wei Liu, Jennifer Lippincott-Schwartz
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Structure and Heterogeneity of the COPII Coat
Microscopy and Microanalysis, 2012Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.
J. O'Donnell +5 more
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In Vitro Reconstitution of Plant COPII Vesicles
In vitro reconstitution studies enable the controllable and stepwise investigation of complicated biochemical processes. In yeast and mammals, in vitro reconstitution of COPII vesicles marked a pivotal point in characterizing the endoplasmic reticulum-to-Golgi anterograde trafficking route and revealed how vesicles mediate the selective and reliable ...Baiying, Li, Liwen, Jiang
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ER export: public transportation by the COPII coach
Current Opinion in Cell Biology, 2001Bruno Antonny, Randy Schekman
exaly