Results 161 to 170 of about 1,214 (239)

Astrocyte Proximity Protects Synapses From Human Amyloid‐Beta Induced Degeneration in a Mouse Ex Vivo Model of Early Alzheimer's Disease

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 7, April 2026.
Alzheimer's disease (AD) is the most common cause of dementia, affecting over 35 million people worldwide. A key feature of AD is the loss of synapses—the connections between brain cells—which strongly correlates with cognitive decline. We sought to investigate the role of astrocytes in mouse organotypic cultures challenged with brain homogenate (BH ...
Francesco Gobbo   +11 more
wiley   +1 more source

A Qualitative Study on Variation in the Written Argumentation of Finnish Final‐Stage Undergraduate Students

open access: yesHigher Education Quarterly, Volume 80, Issue 2, April 2026.
ABSTRACT Higher education students need generic skills such as written argumentation to succeed in their studies and in modern working life. However, research has shown that some students struggle with these skills even at later stages of higher education.
Kaisa Silvennoinen   +3 more
wiley   +1 more source

DNA methylation as a predictor of pituitary neuroendocrine tumour behaviour: A systematic review

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Abstract Pituitary neuroendocrine tumours (PitNETs) range from slow‐growing to highly aggressive tumours; however, traditional prognostic markers often fail to predict clinical outcomes reliably. DNA methylation has recently emerged as a promising biomarker for assessing tumour behaviour. This systematic review evaluates its predictive value in PitNETs.
Romy van der Groef   +3 more
wiley   +1 more source

Commitment to Myogenic Differentiation Significantly Aggravates the RNA Phenotype in Myotonic Dystrophy Type 1

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 2, April 2026.
DM1 myoblasts show mild defects, but RNA toxicity intensifies upon differentiation, where broad gene‐expression changes and escalating MBNL1‐driven splicing defects disrupt muscle‐specific pathways, underscoring a key vulnerability at the transition from myogenic precursor cells to myofibres in patients. ABSTRACT Aims Myotonic dystrophy type 1 (DM1) is
Lise Ripken   +6 more
wiley   +1 more source

Artificial intelligence and machine learning approaches for patient safety in complex surgery: a review. [PDF]

open access: yesPatient Saf Surg
Ahmed MM   +9 more
europepmc   +1 more source

AI in the Classroom: Observing Preclinical Students' Use of ChatGPT During Case‐Based Learning at a UK Medical School

open access: yesThe Clinical Teacher, Volume 23, Issue 2, April 2026.
ABSTRACT Background This article explores how preclinical students in a UK medical school utilise ChatGPT during their case‐based learning (CBL) curriculum. Materials and Methods Focused ethnography was used to study 42 medical students and three clinical sciences students as they undertook seven CBL sessions over 4 weeks.
A. W. R. Taylor   +4 more
wiley   +1 more source

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