Research and Review of Polymethyl-Methacrylate Copolymers in the Development of Enhanced Pharmaceutical Delivery Systems [PDF]
The following thesis shall primarily explore the current research regarding the implementation of modifiable microscopic and nanoscopic polymer particles as novel pharmaceutical delivery systems. Polymethacrylate-based copolymers, such as EudragitTM, are
Dyess, Jake
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xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Multicompartment thermoresponsive gels: Does the length of the hydrophobic side group matter? [PDF]
Multicompartment thermoresponsive gels are novel materials with fascinating self-assembly and interesting applications. The aim of this study was to investigate for the first time the effect of the length of the alkyl side group of a hydrophobic monomer ...
Georgiou, Theoni K., Ward, Mark A.
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In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez +4 more
wiley +1 more source
Macroporous copolymer networks
Macroporous copolymer networks form as a result of the phase separation during the free-radical crosslinking copolymerization of vinyl and divinyl monomers in the presence of an inert diluent. In this article, the develop- ments achieved in the field of macroporous networks over the last few years are presented.
openaire +3 more sources
Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.
Michèle Clerc +9 more
wiley +1 more source
Dielectric and dynamic mechanical study of the mobility of poly(t-butylacrylate) chains in diblock copolymers: polystyrene-b-poly(t-butylacrylate) [PDF]
A calorimetric, dielectric and dynamic-mechanical study of the dynamics of the poly(t-butyl acrylate) (PtBa) chains has been carried out in a PtBa homopolymer and two polystyrene (PS)-b-PtBa block copolymers with different PtBa chain lengths.
Encinar del Pozo, Mario +7 more
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Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
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Easy orientation of diblock copolymers on self-assembled monolayers using UV irradiation
A simple method based on UV/ozone treatment is proposed to control the surface energy of dense grafted silane layers for orientating block copolymer mesophases. Our method allows one to tune the surface energy down to a fraction of a mN/m.
Jean Daillant +3 more
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Biodegradability and biocompatibility of copoly(butylene sebacate-co-terephthalate)s [PDF]
In the present study poly (butylene sebacate-co-terephthalate)s having different compositions were synthesized with a high yield and a random distribution by thermal transesterification of poly (butylene sebacate) and poly (butylene terephthalate ...
Faramarz Afshar Taromi, Faramarz Afshar +5 more
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