Results 51 to 60 of about 601,753 (251)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

The thermodynamic chemistry of the aqueous copper-ammonia thiosulfate system [PDF]

, 2006
A fundamental thermodynamic study was undertaken in order to establish the speciation of copper(I) and copper(II) during the leaching and recovery of gold from thiosulfate-copper-ammonia solutions. Despite considerable research into this complex leaching
Black, Silvia Beatriz
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Breast cancer supplemental screening: Women’s knowledge and utilization in the era of dense breast legislation

Cancer Medicine, 2020
Background Given the growth in dense breast notification (DBN) legislation in the United States, we examined the association between different types of DBN laws and supplemental screening behaviors among women.
Jenerius A. Aminawung, Jessica R. Hoag, Kelly A. Kyanko, Xiao Xu, Ilana B. Richman, Susan H. Busch, Cary P. Gross   +6 more
doaj   +1 more source

A Comparative Study on the Condensation Heat Transfer of R-513A as an Alternative to R-134a

Machines, 2021
This paper presents the two-phase condensation heat transfer and pressure drop characteristics of R-513A as an alternative refrigerant to R-134a in a 9.52-mm OD horizontal microfin copper tube.
Andreas Karageorgis, George Hinopoulos, Man-Hoe Kim   +2 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Automated Surface Defect Detection in Copper Blanks Using YOLOv8 Segmentation and EfficientNetV2-S Classification [PDF]

Journal of Artificial Intelligence and Data Mining
In this study, an intelligent deep learning–based system is proposed for automated detection of surface defects in copper cathode blanks used in the electrorefining process.
Hossein Ghayoumi Zadeh, Ali Fayazi, khosro rezaee, Afsaneh Aminaee, Hadi Halavati, Mehdi Tahernejad, Hadi Memarzadeh, Ali Masoumi, Mohammad Sadegh Jafari   +8 more
doaj   +1 more source

Biomolecular Mode of Action of Metformin in Relation to Its Copper Binding Properties [PDF]

, 2014
Metformin (Metf), the most commonly used type 2 diabetes drug, is known to affect the cellular housekeeping of copper. Recently, we discovered that the structurally closely related propanediimidamide (PDI) shows a cellular behavior different from that of
Paterson, Martin J; id_orcid, Rena, Graham; id_orcid, Erhardt, Stefan, Repiscak, Peter, Rena, Graham, Paterson, Martin J.   +5 more
core   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source