Results 1 to 10 of about 6,779 (214)

Scientometric Analysis of Medicinal and Edible Plant Coptis [PDF]

Frontiers in Pharmacology, 2021
Objective: A scientometric analysis to obtain knowledge mapping of Coptis revealed the current research situation, knowledge base and research hotspots in Coptis research.Methods:Coptis-related documents published from 1987 to 2020 were selected through ...
Zhibang Huang, Zhengkun Hou, Fengbin Liu, Fengbin Liu, Mei Zhang, Wen Hu, Shaofen Xu   +6 more
doaj   +5 more sources

1H-NMR-Based Metabonomics of the Protective Effect of Coptis chinensis and Berberine on Cinnabar-Induced Hepatotoxicity and Nephrotoxicity in Rats

Molecules, 2017
Coptis chinensis Franch has been used in Traditional Chinese Medicine (TCM) for treating infectious and inflammatory diseases for over two thousand years. Berberine (BN), an isoquinoline alkaloid, is the main component of Coptis chinensis.
Guangyue Su, Haifeng Wang, Yuxian Gao, Gang Chen, Yuehu Pei, Jiao Bai   +5 more
doaj   +4 more sources

Altitudinal changes induce responses in Coptis chinensis Franch. rhizomes: endophytic communities, metabolite types, and alkaloid contents [PDF]

Frontiers in Plant Science
Coptis chinensis Franch. is a perennial medicinal plant with huge economic and social benefits, but how altitude affects the accumulation of bioactive compounds through microbial ecosystems remains unexplored.
Wenli Zhang, Wenli Zhang, Yanan Tang, Yanan Tang, Ran Luo, Ran Luo, Jiang He, Jiang He, Jie Yan, Fei Long, Longyun Li   +10 more
doaj   +3 more sources

Study on the Mechanism of Coptis Chinensis in the Treatment of Diabetic Nephropathy Based on Network Pharmacology [PDF]

BIO Web of Conferences, 2023
To investigate the therapeutic effects of Coptis chinensis on diabetic nephropathy using systematic pharmacological techniques. The TCMSP database was used to search the main components and related targets of Coptis chinensis; the GeneCards and CTD ...
Yu Cheng, Qian Liting, Chen Ying, Guan Jing, Jiang Shuang, Song Danning   +5 more
doaj   +2 more sources

The differences in hypoglycemic activity of Coptis herb pairs fermented by Eurotium cristatum and its regulatory effect on gut microbiota in T2DM rats [PDF]

Frontiers in Microbiology
Coptidis Rhizoma-Scutellariae Radix, Coptidis Rhizoma-Glycyrrhizae Radix et Rhizoma, and Coptidis Rhizoma-Panax notoginseng are herbal pairs widely used in clinical therapy for Type 2 Diabetes Mellitus (T2DM) and gastrointestinal diseases.
Yanli Wang, Yanli Wang, Yincui Chen, Anqin Zhu, Jin Zhang, Shiping Lu, Chuanbo Zhang   +6 more
doaj   +2 more sources

Evolutionary history of genus Coptis and its dynamic changes in the potential suitable distribution area

Frontiers in Plant Science, 2022
The genus Coptis belongs to the Ranunculaceae family, containing 15 recognized species highly diverse in morphology. It is a conspicuous taxon with special evolutionary position, distribution pattern and medicinal value, which makes it to be of great ...
Yiheng Wang, Yiheng Wang, Jiahui Sun, Ping Qiao, Jingyi Wang, Mengli Wang, Yongxi Du, Yongxi Du, Feng Xiong, Feng Xiong, Jun Luo, Qingjun Yuan, Wenpan Dong, Luqi Huang, Lanping Guo, Lanping Guo   +15 more
doaj   +3 more sources

Coptis alkaloids improve gluconeogenesis and lipid accumulation in mouse primary hepatocytes [PDF]

Jichu yixue yu linchuang, 2023
Objective To screen the alkaloid monomer of coptis chinensis, which can improve the gluconeogenesis and lipid accumulation of mouse primary hepatocytes, and to explore its mechanism.Methods The mouse primary hepatocytes were isolated and incubated with ...
YAN Jiaqi, WANG Siqi, WANG Zheng, LI Jun
doaj   +2 more sources

Population genetic variation and geographic distribution of suitable areas of Coptis species in China

Frontiers in Plant Science
IntroductionThe rhizomes of Coptis plants have been used in traditional Chinese medicine over 2000 years. Due to increasing market demand, the overexploitation of wild populations, habitat degradation and indiscriminate artificial cultivation of Coptis ...
Yujie Chi, Changli Liu, Wei Liu, Xufang Tian, Juan Hu, Bo Wang, Di Liu, Yifei Liu, Yifei Liu   +8 more
doaj   +3 more sources

Variation in the Efficacy of Anti-Ulcerative Colitis Treatments Reveals the Conflict Between Precipitating Compatibility of Traditional Chinese Medicine and Modern Technology: A Case of Scutellaria-Coptis

Frontiers in Pharmacology, 2022
Scutellariae and Coptidis compose a classical drug pair applied in clinical practice to dispel heat, dryness, and dampness, and they are also precipitation compatible drug pairs.
Dan Liu, Ran Zhao, Yajing Wu, Yunhong Wang, Rongping Yang, Xiumei Ke, Xiumei Ke   +6 more
doaj   +1 more source

Thioredoxin/Glutaredoxin Systems and Gut Microbiota in NAFLD: Interplay, Mechanism, and Therapeutical Potential

Antioxidants, 2023
Non-alcoholic fatty liver disease (NAFLD) is a common clinical disease, and its pathogenesis is closely linked to oxidative stress and gut microbiota dysbiosis.
Minghui Zhu, Omer M. A. Dagah, Billton Bryson Silaa, Jun Lu   +3 more
doaj   +1 more source