Results 71 to 80 of about 6,779 (214)

Colon‐Targeted Berberine Nanoparticles‐Embedded Yeast Microcapsules for Regulation of Gut Immunity of Sepsis

eFood, Volume 7, Issue 4, August 2026.
A schematic representation illustrating the preparation of BGNP@YM and its therapeutic effects on septic mice induced by lipopolysaccharide (LPS). (A) BBR is first encapsulated within GNPs to form BGNPs with anti‐inflammatory activity, which are subsequently coated with YM via chemical precipitation to obtain the BGNP@YM oral delivery system.
Qing‐Qing Dong, Si‐Hui Wang, Chen‐Yan Wang, Ke‐Da Yang, Xiao‐Ling Xu, Yi Shi, Wei Chen   +6 more
wiley   +1 more source

Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak, Rachael Moorin, Jeff Hughes, Karl Gruber, David Youens   +4 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Effect of herbal extracts on peripheral nerve regeneration after microsurgery of the sciatic nerve in rats

BMC Complementary Medicine and Therapies, 2021
Background Recent experimental studies using herbal extracts have shown the possibility of peripheral nerve regeneration. This study aimed to investigate the effects of herbal extracts on peripheral nerve regeneration in a rat sciatic nerve injury model.
Young Jun Kim, Kyu Jin Kim, Jae Hoon Lee, Seong-Uk Park, Seung-Yeon Cho   +4 more
doaj   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4823-4843, August 2026.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

In vitro inhibition of five Chinese herbal extracts and their combinations against Aeromonas hydrophila

Siliao yanjiu, 2023
The study investigated the in vitro inhibitory effect of five Chinese herbals including Rhubarb, Terminalia chebula Retz,Galla chinensis,Coptis chinensis and Scutellaria baicalensis, and their combinations on Aeromonas hydrophila.
WANG Shuai-bing, ZHANG Ya-cheng
doaj  

Extracts from Traditional Chinese Medicinal Plants Inhibit Acetylcholinesterase, a Known Alzheimer’s Disease Target

Molecules, 2016
Inhibition of acetylcholinesterase (AChE) is a common treatment for early stages of the most general form of dementia, Alzheimer’s Disease (AD). In this study, methanol, dichloromethane and aqueous crude extracts from 80 Traditional Chinese Medical (TCM)
Dorothea Kaufmann, Anudeep Kaur Dogra, Ahmad Tahrani, Florian Herrmann, Michael Wink   +4 more
doaj   +1 more source

Advances in the Study of Endometrial Receptivity and Glucose Metabolism Mechanisms in Insulin Resistance

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang, Shao‐rong Chen, Wei‐hong Chen, Ling‐tao Zheng, Jing Xu, Yan‐Chuan Shi, Shu Lin, Qi‐rong Shi   +7 more
wiley   +1 more source

Biosynthesis and regulatory mechanisms of benzylisoquinoline alkaloids in medicinal plants

Medicinal Plant Biology
Benzylisoquinoline alkaloids (BIAs) derived from Coptis species, opium poppy, and California poppy have been demonstrated to cure various diseases. Historically, Coptis species, opium poppy, and California poppy have served as models for the study of ...
Lingyue Qin, Yanxia Liu, Qianliang Ming, Peng Li   +3 more
doaj   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid, Ifrah Jabeen, Muhammad Inam‐ur‐Raheem, Amin Mousavi Khaneghah, Muhammad Abid, Rana Muhammad Aadil   +5 more
wiley   +1 more source