Results 211 to 220 of about 44,033 (313)

Adaptive Seamless Phase II/III Randomization Test Considering Treatment Group Selection Based on Short–Term Binary Outcomes

open access: yesStatistics in Medicine, Volume 45, Issue 3-5, February 2026.
ABSTRACT Recently, adaptive seamless phase II/III designs (ASDs) have gained attention because they improve the efficiency of drug development. In an ASD, a phase II trial, which explores the dose–response relationships and identifies treatments for the phase III trial, is combined with a phase III trial, which aims to demonstrate the efficacy and ...
Funato Sato   +4 more
wiley   +1 more source

Runoff Reconstructions and Future Projections Indicate Highly Variable Water Supply From Pacific Rim Water Towers

open access: yesAGU Advances, Volume 7, Issue 1, February 2026.
Abstract Anthropogenic climate change affects regional hydrological cycles and poses significant challenges to the sustainable supply of freshwater. The Central China water tower (CCWT) is the key source region feeding the Yangtze and Yellow Rivers, and its runoff is indispensable for the surrounding mega‐city clusters. Here we present a reconstruction
Weipeng Yue   +18 more
wiley   +1 more source

Pickpocket315 affects male mating behavior in the yellow fever mosquito Aedes aegypti. [PDF]

open access: yesG3 (Bethesda)
Wyer CAS   +7 more
europepmc   +1 more source

Evaluating the Performance of Uni‐ and Multivariate Bias Correction Techniques: Challenges in Preserving Temporal and Dependence Structures

open access: yesWater Resources Research, Volume 62, Issue 2, February 2026.
Abstract Global Climate Models (GCMs) are essential for simulating past and future climates but suffer from systematic biases and coarse resolution, limiting direct applications. Bias correction (BC) and downscaling, using dynamical or statistical methods, address these issues. Quantile mapping (QM)‐based BC is widely used, yet it distorts dependencies,
Sachidananda Sharma   +2 more
wiley   +1 more source

A Synthetic European Weather Dataset Based on Spatiotemporal Vine Copulas. [PDF]

open access: yesSci Data
Claassen JN   +4 more
europepmc   +1 more source

Informational Efficiency in Cryptocurrency Markets: A Bibliometric and Thematic Literature Review (2015–2024)

open access: yesJournal of Economic Surveys, Volume 40, Issue 1, Page 443-468, February 2026.
ABSTRACT Cryptocurrency markets are known for their wide price fluctuations, lack of central control, and fast‐paced development. These characteristics present serious challenges to traditional theories about how markets work and how prices reflect available information.
Giulia Fantini, Joy Jia, Chiara Oldani
wiley   +1 more source

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