Results 171 to 180 of about 1,208,876 (310)

Transcriptional capacity limits copper resistance in yeast harboring highly expanded <i>CUP1</i> arrays. [PDF]

MicroPubl Biol
Takesue H, Okada S, Ito T.
europepmc   +1 more source

Copy rules to copy [PDF]

Nature, 1988
openaire   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

DNA copy number patterns reveal prognostic markers and elucidate mechanisms of evolution in IDH-mutant astrocytoma. [PDF]

Neuro Oncol
Drucker KL, Panda A, Decker PA, Kosel ML, Kollmeyer TM, Burns TC, Maqbool MA, Shafqat S, Suvakov M, Zadeh G, Giannini C, Vaubel R, Raghunathan A, Parney IF, Kizilbash SH, Ida CM, Abyzov A, Lachance DH, Eckel-Passow JE, Jenkins RB.   +19 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Rapid adaptive increase of amylase gene copy number in Indigenous Andeans. [PDF]

Nat Commun
Scheer K, Landau LJB, Jorgensen K, Karageorgiou C, Siao L, Alkan C, Morales Rivera AM, Osborne C, Garcia OA, Pearson L, Kiyamu M, Rivera-Ch M, León-Velarde F, Lee FS, Brutsaert T, Bigham AW, Gokcumen O.   +16 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Genomic Basis of Zoonotic Transmission and Antifungal Resistance in <i>Microsporum canis</i>. [PDF]

J Fungi (Basel)
Du Z, Zhang Y, Meng X, Lv Z, Wang Y, Wu C.   +5 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Activity of DNA- and RNA-Guided Prokaryotic Argonautes in Human Mitochondria. [PDF]

Cells
Rimskaya B, Kropocheva E, Ponomareva I, Karchemkina L, Lisitskaya L, Gelfenbein D, Ulashchik E, Shmanai V, Kulbachinskiy A, Mazunin I.   +9 more
europepmc   +1 more source