Results 241 to 250 of about 1,695,985 (356)

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Supplementary Material for: LPA and PLG Sequence Variation and Kringle IV-2 Copy Number in Two Populations

, 2008
Dana C. Crawford, Ze Peng, Jan‐Fang Cheng, Dario Boffelli, Mary Ellen Ahearn, David N. Nguyen, Tristan Shaffer, Yi Qian, Robert Livingston, Mark J. Rieder   +9 more
openalex   +2 more sources

Genetic diversity and population structure of the Taigan dog breed

FEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova, Anastassiya Perfilyeva, Мamura Begmanova, Assel Zhaxylykova, Arailym Yerzhan, Kanagat Yergali, Almazbek Akunov, Marat Munarbek uulu, Anna Khamchukova, Almira Amirgaliyeva, Yelena Kuzovleva   +10 more
wiley   +1 more source

A Comprehensive Workflow for Read Depth-Based Identification of Copy-Number Variation from Whole-Genome Sequence Data.

American Journal of Human Genetics, 2018
B. Trost, S. Walker, Zhuozhi Wang, B. Thiruvahindrapuram, J. MacDonald, W. Sung, S. Pereira, J. Whitney, A. Chan, G. Pellecchia, M. Reuter, S. Lok, R. Yuen, C. Marshall, D. Merico, S. Scherer   +15 more
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

A copy number variation detection method based on OCSVM algorithm using multi strategies integration. [PDF]

Sci Rep
Zhou M, Dong J, Jiang H, Zhao Z, Yuan T.
europepmc   +1 more source

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

, 2009
P. J. Hastings, Grzegorz Ira, James R. Lupski   +2 more
openalex   +2 more sources

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee, Subha Perni, Kelly J. Perrin, Kevin E. Casey, Alexandra O. Leone, Callistus M. Nguyen, Laurence E. Court, He Wang, Xin Wang, Eun Young Han   +9 more
wiley   +1 more source

Establishing a prognostic threshold for total copy number variation within adult IDH-mutant grade II/III astrocytomas

Acta Neuropathologica Communications, 2019
Kanish Mirchia, Matija Snuderl, Kristyn Galbraith, Kimmo J. Hatanpaa, Jamie M. Walker, Timothy E. Richardson   +5 more
doaj   +1 more source

Copy Number Variation Shapes Genome Diversity in Arabidopsis Over Immediate Family Generational Scales [PDF]

, 2010
Seth DeBolt
openalex   +1 more source