Results 91 to 100 of about 75,676 (211)
GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer
Advanced Science, Volume 13, Issue 23, 23 April 2026.This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier +16 more
wiley +1 more source
Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation
Advanced Science, Volume 13, Issue 23, 23 April 2026.The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley +1 more source
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
eLife, 2018 Insulin resistance in muscle, adipocytes and liver is a gateway to a number of metabolic diseases. Here, we show a selective deficiency in mitochondrial coenzyme Q (CoQ) in insulin-resistant adipose and muscle tissue.
Daniel J Fazakerley +23 more
doaj +1 more source
, 1996 The essential step of the formal verification of a proof-checker such as Coq is the verification of its kernel: a type-checker for the Calculus of Inductive Constructions (CIC) which is its underlying formalism. The present work is a first small-scale attempt on a significative fragment of CIC: the Calculus of Constructions (CC).
openaire +2 more sources
Modal Linear Logic in Higher Order Logic, an experiment in Coq
, 2003 The sequent calculus of classical modal linear logic KDT 4lin is coded in the higher order logic using the proof assistant COQ. The encoding has been done using two-level meta reasoning in Coq.
Sadrzadeh, Mehrnoosh
core +1 more source
Negotiation tools for vegetable commodity chain in Vientiane : SUSPER (sustainable development of peri-urban agriculture in South-East Asia) project [PDF]
, 2003 This report gives an overview of the vegetable sector in Vientiane prefecture in terms of production and market (supply and demand). The report is based on secondary data (see bibliography) and some preliminary results from the analysis of the data ...
Le Coq, Jean-François
core
SEPIA: Search for Proofs Using Inferred Automata
, 2015 This paper describes SEPIA, a tool for automated proof generation in Coq. SEPIA combines model inference with interactive theorem proving. Existing proof corpora are modelled using state-based models inferred from tactic sequences.
F Wiedijk +6 more
core +1 more source
Coenzyme Q in the Treatment of Mitochondrial Disease
Journal of Inborn Errors of Metabolism and Screening, 2017 Currently, there is a paucity of available treatment strategies for oxidative phosphorylation disorders. Coenzyme Q 10 (CoQ 10 ) and related synthetic quinones are the only agents to date that have proven to be beneficial in the treatment of these ...
Viruna Neergheen MSc +6 more
doaj +1 more source
Explaining Gabriel-Zisman localization to the computer [PDF]
, 2005 This explains a computer formulation of Gabriel-Zisman localization of categories in the proof assistant Coq. It includes both the general localization construction with the proof of GZ's Lemma 1.2, as well as the construction using calculus of fractions.
Simpson, Carlos T.
core +3 more sources
Journal of Automated Reasoning, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources