Results 11 to 20 of about 4,702,161 (344)

Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios.

JAMA pediatrics, 2021
Importance Maternally derived antibodies are a key element of neonatal immunity. Understanding the dynamics of maternal antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and subsequent ...
D. Flannery, S. Gouma, Miren B Dhudasia, S. Mukhopadhyay, M. Pfeifer, E. Woodford, Jourdan E. Triebwasser, J. Gerber, Jeffrey S. Morris, M. Weirick, C. McAllister, M. Bolton, C. P. Arevalo, E. M. Anderson, E. Goodwin, S. Hensley, K. Puopolo   +16 more
semanticscholar   +1 more source

Antibody Response to Coronavirus Disease 2019 (COVID-19) Messenger RNA Vaccination in Pregnant Women and Transplacental Passage Into Cord Blood

Obstetrics and Gynecology, 2021
Coronavirus disease 2019 (COVID-19) vaccination in pregnancy induces a robust maternal immune response, with transplacental antibody transfer detectable in cord blood as early as 16 days after the first dose.
M. Prabhu, Elisabeth A. Murphy, A. Sukhu, J. Yee, Sunidhi Singh, Dorothy Eng, Zhen Zhao, L. Riley, Yawei J. Yang   +8 more
semanticscholar   +1 more source

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells.

Blood, 2020
Immune checkpoint therapy has resulted in remarkable improvements in the outcome for certain cancers. To broaden the clinical impact of checkpoint targeting, we devised a strategy that couples targeting of the cytokine-inducible SH2-containing (CIS ...
M. Daher, R. Başar, Elif Gokdemir, Natalia Baran, N. Uprety, A. N. Nunez Cortes, Mayela Mendt, L. Kerbauy, P. Banerjee, M. Shanley, N. Imahashi, Li Li, F. Lim, Mohsen Fathi, A. Rezvan, Vakul Mohanty, Yifei Shen, Hila Shaim, Junjun Lu, Gonca Ozcan, Emily Ensley, Mecit Kaplan, Vandana Nandivada, Mustafa H Bdiwi, S. Acharya, Y. Xi, Xinhai Wan, D. Mak, E. Liu, X. Jiang, S. Ang, Luis Muniz-Feliciano, Ye Li, Jing Wang, S. Kordasti, N. Petrov, N. Varadarajan, D. Marin, L. Brunetti, R. J. Skinner, Shangrong Lyu, Leiser Silva, R. Turk, Mollie S. Schubert, G. Rettig, Matthew S. McNeill, G. Kurgan, M. Behlke, Heng Li, N. Fowlkes, Ken Chen, M. Konopleva, R. Champlin, E. Shpall, K. Rezvani   +54 more
semanticscholar   +1 more source

Double unrelated umbilical cord blood versus HLA-haploidentical bone marrow transplantation (BMT CTN 1101).

Blood, 2020
Results of two parallel phase II trials of transplantation of unrelated umbilical cord blood or bone marrow from HLA-haploidentical relatives provided equipoise for direct comparison of these donor sources.
E. Fuchs, P. O'Donnell, M. Eapen, B. Logan, J. Antin, P. Dawson, S. Devine, M. Horowitz, M. Horwitz, C. Karanes, E. Leifer, J. Magenau, J. Mcguirk, L. Morris, Andrew R. Rezvani, Richard J. Jones, C. Brunstein   +16 more
semanticscholar   +1 more source

Cord blood banking: ‘providing cord blood banking for a nation’ [PDF]

British Journal of Haematology, 2009
SummaryTransplantation of cord blood (CB) is increasingly used as therapy for patients whose own marrow is affected by genetic mutations that prevent the development of normal cells of the blood or immune tissues, or for patients whose marrow has been destroyed in the course of treatment for leukaemia and other malignancies.
Sergio Querol, JA Madrigal, Steven G.E. Marsh, Pablo Rubinstein, John Goldman   +4 more
openaire   +3 more sources

Clinical Outcomes of Unrelated Umbilical Cord Blood Graft vs. Haploidentical Donor Transplantation: Critical Issues for an Adequate Comparison

Frontiers in Medicine, 2021
Unrelated umbilical cord blood (UCB) and haploidentical grafts have been used for allogeneic hematopoietic stem and progenitor cell (HSPC) transplantation in patients without a related or non-related human leukocyte antigen (HLA)-matched donor.
Diana Vanegas, Laura Niño-Quiroga, Mauricio Chaparro, Bernardo Camacho-Rodríguez, Marcela Estupiñán, Ana-María Perdomo-Arciniegas   +5 more
doaj   +1 more source

Mitochondrial Cardiomyopathy: Molecular Epidemiology, Diagnosis, Models, and Therapeutic Management

Cells, 2022
Mitochondrial cardiomyopathy (MCM) is characterized by abnormal heart-muscle structure and function, caused by mutations in the nuclear genome or mitochondrial DNA.
Jinjuan Yang, Shaoxiang Chen, Fuyu Duan, Xiuxiu Wang, Xiaoxian Zhang, Boonxuan Lian, Meng Kou, Zhixin Chiang, Ziyue Li, Qizhou Lian   +9 more
doaj   +1 more source

Umbilical cord blood transplantation [PDF]

Korean Journal of Pediatrics, 2012
Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful ...
Hong Hoe Koo, Hyo Seop Ahn
openaire   +4 more sources

Evaluation of the Regenerative Potential of Platelet-Lysate and Platelet-Poor Plasma Derived from the Cord Blood Units in Corneal Wound Healing Applications: An In Vitro Comparative Study on Corneal Epithelial Cells

Current Issues in Molecular Biology, 2022
Background: Cord blood platelet lysate (CB-PL) and cord blood platelet poor plasma (CB-PPP) have been applied with success in wound healing applications.
Panagiotis Mallis, Efstathios Michalopoulos, Eirini Faidra Sarri, Elena Papadopoulou, Vasiliki Theodoropoulou, Michalis Katsimpoulas, Catherine Stavropoulos-Giokas   +6 more
doaj   +1 more source

Cord-Blood Transplantation in Patients with Minimal Residual Disease.

New England Journal of Medicine, 2016
BackgroundThe majority of patients in need of a hematopoietic-cell transplant do not have a matched related donor. Data are needed to inform the choice among various alternative donor-cell sources.
F. Milano, F. Appelbaum, C. Delaney
semanticscholar   +2 more sources