Results 261 to 270 of about 4,702,161 (344)

Research advances in dysphagia animal models

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai, Keling Cheng, Nannan Zhang, Yunfang Chen, Jun Ni, Zhiyong Wang   +5 more
wiley   +1 more source

Antiretroviral-Induced Toxicity in Umbilical Cord Blood-Derived Haematopoietic Stem/Progenitor Cells. [PDF]

J Cell Mol Med
Hendricks CL, Ellero A, Mellet J, Stivaktas V, Pepper MS.   +4 more
europepmc   +1 more source

The Impact of Tirabrutinib Monotherapy for the Treatment of Bing‐Neel Syndrome: A Multicenter Retrospective Study

American Journal of Hematology, EarlyView.
Masuho Saburi, Taro Masunari, Noriko Fukuhara, Yuichiro Inagaki, Arika Shimura, Naoto Imoto, Yuta Hasegawa, Masao Hagihara, Nobuhiko Kobayashi, Hanae Kumekawa, Hideyuki Nakazawa, Kana Miyazaki, Toshiro Kawakita, Takahiro Isshiki, Atsushi Katsube, Shin Fujisawa, Yuichi Horigome, Yusuke Koba, Fumiaki Jinnouchi, Naohiro Sekiguchi   +19 more
wiley   +1 more source

A comparative study of human ovarian tissue xenotransplantation in two different strains of rats

Animal Models and Experimental Medicine, EarlyView.
The study involved performing ovariectomy on female Hooded and Wistar rats 14 days prior to transplantation. Following ovariectomy, the rats received cyclosporine starting five days before surgery to suppress the immune response and prevent graft rejection.
Mohammad Ayoubipour, Hussein Eimani, Rouhollah Fathi, Mohammad Kazemi Ashtiani, Ashraf Moinie, Parviz Golmohammadi Gerdkohi   +5 more
wiley   +1 more source

Randomized, Double‐Blind, Placebo‐Controlled, Multiple‐Dose Studies to Assess the Safety and Efficacy of Elezanumab when Added to Standard of Care in Relapsing and Progressive Forms of Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Elezanumab is a monoclonal antibody that binds repulsive guidance molecule a (RGMa), an inhibitor of central nervous system regeneration after inflammation or injury. The aim was to assess the safety and efficacy of elezanumab in relapsing and progressive forms of multiple sclerosis (MS).
Bruce A.C. Cree, Mark S. Freedman, Michael Gold, Kimberly Pfleeger, Brittany Schwefel, Annette Wundes, Adam Ziemann   +6 more
wiley   +1 more source

High‐Dose Pulse Glucocorticoid Treatment Prevents White Matter Spinal Cord Pseudoatrophy in Newly Diagnosed Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Spinal cord (SC) atrophy correlates with and predicts the underlying progressive biology in active and non‐active multiple sclerosis (MS), thereby providing a biomarker for clinical trials and patient management. Initiation of disease‐modifying therapy (DMT) may be followed by early pronounced central nervous system (CNS) volume loss due to ...
Simone Sacco, Nico Papinutto, Vinicius A. Schoeps, Shuiting Cheng, William A. Stern, Haojun Zhao, Antje Bischof, Eduardo Caverzasi, Manula Dombagahawatta, Jeremy Juwono, Amit Akula, Christian Cordano, Alexandra Beaudry‐Richard, Refujia Gomez, Meagan Harms, Adam Santaniello, Riley M. Bove, Jeffrey M. Gelfand, Douglas S. Goodin, Ari J. Green, Jorge R. Oksenberg, Emmanuelle Waubant, Michael R. Wilson, Scott S. Zamvil, Bruce A. C. Cree, Stephen L. Hauser, Roland G. Henry   +26 more
wiley   +1 more source

Machine learning-based prediction of preterm birth risk using methylation changes in neonatal cord blood CpG sites. [PDF]

BMC Pregnancy Childbirth
Feng Y, Ni Y, Wang W, Guo F, Wang L, Zhu F, Zhang L, Feng Y.   +7 more
europepmc   +1 more source

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids

Annals of Neurology, EarlyView.
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler, Matthew C. Kiernan, Rachel H. Tan   +2 more
wiley   +1 more source

Sexual dimorphism in the association of umbilical cord blood lipidome with abdominal fat in early childhood. [PDF]

BMC Med
Narasimhan K, Tint MT, Chen L, Mir SA, Sadananthan SA, Michael N, Ramasamy A, Tan KM, Mishra P, Bendt AK, Tan KH, Cameron-Smith D, Chong YS, Gluckman PD, Meikle PJ, Leow MKS, Yap F, Lee YS, Yng CS, Eriksson JG, Velan SS, Karnani N, Wenk MR.   +22 more
europepmc   +1 more source