Mitochondrial Cardiomyopathy: Molecular Epidemiology, Diagnosis, Models, and Therapeutic Management
Mitochondrial cardiomyopathy (MCM) is characterized by abnormal heart-muscle structure and function, caused by mutations in the nuclear genome or mitochondrial DNA.
Jinjuan Yang+9 more
doaj +1 more source
Distance to healthy cardiovascular dynamics from fetal heart rate scale-dependent features in pregnant sheep model of human labor predicts cardiovascular decompensation [PDF]
The overarching goal of the present work is to contribute to the understanding of the relations between fetal heart rate (FHR) temporal dynamics and the well-being of the fetus, notably in terms of predicting cardiovascular decompensation (CVD).
arxiv +1 more source
Umbilical cord blood transplantation [PDF]
Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful ...
Hong Hoe Koo, Hyo Seop Ahn
openaire +4 more sources
Background: Cord blood platelet lysate (CB-PL) and cord blood platelet poor plasma (CB-PPP) have been applied with success in wound healing applications.
Panagiotis Mallis+6 more
doaj +1 more source
Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. [PDF]
BACKGROUND: Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies.
Cose, Stephen+8 more
core +5 more sources
Cardiovascular disease (CVD) currently represents one of the leading causes of death worldwide. It is estimated that more than 17.9 million people die each year due to CVD manifestations.
Panagiotis Mallis+2 more
doaj +1 more source
DNA methylation and socioeconomic status in a Mexican-American birth cohort. [PDF]
Background: Maternal social environmental stressors during pregnancy are associated with adverse birth and child developmental outcomes, and epigenetics has been proposed as a possible mechanism for such relationships.
Coker, Eric+4 more
core +1 more source
Cord blood maternal microchimerism following unrelated cord blood transplantation
Cord blood transplantation (CBT) is associated with low risk of leukemia relapse. Mechanisms underlying antileukemia benefit of CBT are not well understood, however a previous study strongly but indirectly implicated cells from the mother of the cord blood (CB) donor.
Alexandra M Forsyth+15 more
openaire +4 more sources
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and multipotent differentiation.
Meng Kou+15 more
doaj +1 more source
Donor selection for allogenic hemopoietic stem cell transplantation: clinical and ethical considerations [PDF]
Allogenic hematopoietic progenitor cell transplantation (allo-HSCT) is an established treatment for many diseases. Stem cells may be obtained from different sources: mobilized peripheral blood stem cells, bone marrow, and umbilical cord blood.
La Russa, Raffaele+5 more
core +4 more sources