Results 41 to 50 of about 686,637 (361)

Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires [PDF]

open access: yesPLoS Comput Biol 13(7): e1005572 (2017), 2016
The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequence rare. Yet unrelated individuals do share receptors, which together constitute a "public" repertoire of abundant clonotypes.
arxiv   +1 more source

DARS2 overexpression is associated with PET/CT metabolic parameters and affects glycolytic activity in lung adenocarcinoma

open access: yesJournal of Translational Medicine, 2023
Background This study investigated the correlation between the expression of DARS2 and metabolic parameters of 18F-FDG PET/CT, and explored the potential mechanisms of DARS2 affecting the proliferation and glycolysis of lung adenocarcinoma (LUAD) cells ...
Xu-Sheng Liu   +8 more
doaj   +1 more source

Optimizing Measurement of Vascular Endothelial Growth Factor in Small Blood Samples of Premature Infants [PDF]

open access: yes, 2019
To establish a method that allows for the reliable assessment of vascular endothelial growth factor (VEGF-A) concentrations in very small blood samples of preterm infants. Systemic VEGF measurements are important in view of the most appropriate Anti-VEGF
Lopez Yomayuza, Claudia C.   +3 more
core   +1 more source

Statistical Analysis of Behavioral Intention Towards Private Umbilical Cord Blood Banking [PDF]

open access: yesarXiv, 2020
In this paper, we propose a conceptual framework to identify the key dimensions affecting behavioral intention to bank umbilical cord blood in Iran. We examine the impact of awareness, reference group, usability, disease history, and price on perceived risk and behavioral intention to use umbilical cord blood banking service.
arxiv  

Family based HLA imputation and optimization of haplo-identical transplants [PDF]

open access: yesarXiv, 2022
Recently, haplo-identical transplantation with multiple HLA mismatches has become a viable option for system cell transplants. Haplotype sharing detection requires imputation of donor and recipient. We show that even in high-resolution typing when all alleles are known, there is a 15% error rate in haplotype phasing, and even more in low resolution ...
arxiv  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Introduction to the Special Issue on Stem Cell and Biologic Scaffold Engineering

open access: yesBioengineering, 2019
Tissue engineering and regenerative medicine is a rapidly evolving research field that effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular
Panagiotis Mallis   +2 more
doaj   +1 more source

Effect of Mesenchymal Stem Cell-derived Microvesicles on Megakaryocytic Differentiation of CD34+ Hematopoietic Stem Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2020
Purpose: Mesenchymal stem cells (MSCs) release hematopoietic cytokines, growth factors, and Microvesicles (MVs) supporting the hematopoietic stem cells (HSCs).
Sara Aqmasheh   +6 more
doaj   +1 more source

Definition of the cord algebra of knots using Morse Theory [PDF]

open access: yesAlgebr. Geom. Topol. 24 (2024) 2971-3042, 2019
We redefine the cord algebra, which was introduced by Lenhard Ng as a topological knot invariant, in terms of Morse Theory. The determination of the cord algebra of the unknot and of the righthanded trefoil are given. We proove that the cord algebra in our definition is a knot invariant.
arxiv   +1 more source

Home - About - Disclaimer - Privacy