Results 71 to 80 of about 4,702,161 (344)

Future Perspectives in Small-Diameter Vascular Graft Engineering

Bioengineering, 2020
The increased demands of small-diameter vascular grafts (SDVGs) globally has forced the scientific society to explore alternative strategies utilizing the tissue engineering approaches. Cardiovascular disease (CVD) comprises one of the most lethal groups
Panagiotis Mallis, Alkiviadis Kostakis, Catherine Stavropoulos-Giokas, Efstathios Michalopoulos   +3 more
doaj   +1 more source

High concentrations of folate and unmetabolized folic acid in a cohort of pregnant Canadian women and umbilical cord blood.

American Journal of Clinical Nutrition, 2015
BACKGROUND Mandatory fortification, prevalent supplement use, and public health guidelines recommending periconceptional supplementation have increased folic acid intakes in North American pregnant women.
L. Plumptre, S. Masih, A. Ly, S. Aufreiter, K. Sohn, R. Croxford, A. Lausman, H. Berger, D. O’Connor, Young-In Kim   +9 more
semanticscholar   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring.

Human Molecular Genetics, 2015
Exposure of a developing foetus to maternal gestational diabetes (GDM) has been shown to programme future risk of diabetes and obesity. Epigenetic variation in foetal tissue may have a mechanistic role in metabolic disease programming through interaction
S. Finer, C. Mathews, R. Lowe, M. Smart, S. Hillman, Lin Foo, A. Sinha, David J. Williams, V. Rakyan, G. Hitman   +9 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Constructing a potential HLA haplo-homozygous induced pluripotent stem cell haplobank using data from an umbilical cord blood bank

Stem Cell Research & Therapy
Background Induced pluripotent stem cells (iPSCs) can differentiate into any type of cell and have potential uses in regenerative medicine for the treatment of many diseases. However, reducing immune rejection is a key problem in the application of iPSCs
Ji He, Yanmin He, Qigang Zhan, Zhipan Wu, Qi Sheng, Wei Zhang, Faming Zhu   +6 more
doaj   +1 more source

Blood GFAP as an emerging biomarker in brain and spinal cord disorders

Nature Reviews Neurology, 2022
A. Abdelhak, M. Foschi, Samir Abu-Rumeileh, J. Yue, L. D’Anna, A. Huss, P. Oeckl, A. Ludolph, J. Kuhle, A. Petzold, G. Manley, A. Green, M. Otto, H. Tumani   +13 more
semanticscholar   +1 more source

Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro

PLoS ONE, 2015
Hypoxic preconditioning was shown to improve the therapeutic efficacy of bone marrow-derived multipotent mesenchymal stromal cells (MSCs) upon transplantation in ischemic tissue. Given the interest in clinical applications of umbilical cord blood-derived
A. Bader, K. Klose, K. Bieback, D. Korinth, M. Schneider, M. Seifert, Yeong-Hoon Choi, A. Kurtz, V. Falk, C. Stamm   +9 more
semanticscholar   +1 more source

Advanced Cellulose‐Based Gels for Wearable Physiological Monitoring: From Fiber Modification to Application Optimization

Advanced Functional Materials, EarlyView.
This review discusses cellulose‐based hydrogels technology, analyzes their application progress in physiological signal monitoring, and explores the effects of pretreatment, crosslinking, and molding methods on gel performance, to provide valuable insights into the efficient utilization of plant fibers and the environmentally friendly development of ...
Zhiming Wang, Jinxuan Jiang, Kexin Wei, Xiaojian Zhou, Muhammad Wakil Shahzad, Yifan Li, Xuehua Zhang, Ben Bin Xu, Shengbo Ge   +8 more
wiley   +1 more source

HLA DRB1 and HLA DQB1 Alleles in Bulgarian Patients with Primary and Secondary Antiphospholipid Syndrome

Acta Medica Bulgarica, 2019
Antiphospholipid syndrome (APS) is an autoimmune disease with multifactorial and polygenic pathogenesis. Recently, the genetic predisposition in APS has been subjected to wide discussion.
Baleva M., Nikolova-Vlahova M., Lukanov Tsv., Ivanova-Shivarova M., Karagjozova Zh., Martinova F., Naumova E.   +6 more
doaj   +1 more source