Results 71 to 80 of about 686,637 (361)
Media(ted) fabrications: How the science-media symbiosis helped ‘sell’ cord banking [PDF]
This paper considers the problematic role of the science–media symbiosis in the dissemination of misleading and emotionally manipulative information regarding services offered by CordBank, New Zealand's only umbilical cord blood banking facility. As this
American College of Physicians+10 more
core +2 more sources
Hematopoietic stem cell transplant (HSCT) can be curative for many cancers and inherited non-malignant diseases, including bone marrow failure syndromes, hemoglobinopathies, and inborn errors of metabolism. While, in most settings, matched sibling transplantation confers best results, more than two-thirds of patients lack a suitable donor.
openaire +2 more sources
The immunobiology of cord blood transplantation [PDF]
Despite significant recent advances in the applicability and outcome following unrelated cord blood transplantation (UCBT), infections remain a major cause of mortality associated with poor immune recovery in the first 6 months after UCBT. Enhanced immune reconstitution not only could improve survival by reduced transplant related mortality, but may ...
openaire +3 more sources
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan+8 more
wiley +1 more source
Automatic breach detection during spine pedicle drilling based on vibroacoustic sensing [PDF]
Pedicle drilling is a complex and critical spinal surgery task. Detecting breach or penetration of the surgical tool to the cortical wall during pilot-hole drilling is essential to avoid damage to vital anatomical structures adjacent to the pedicle, such as the spinal cord, blood vessels, and nerves.
arxiv
Progress toward curing HIV infection with hematopoietic cell transplantation. [PDF]
HIV-1 infection afflicts more than 35 million people worldwide, according to 2014 estimates from the World Health Organization. For those individuals who have access to antiretroviral therapy, these drugs can effectively suppress, but not cure, HIV-1 ...
Armitage, Sue+15 more
core +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Umbilical Cord Blood Banking and its Therapeutic Uses [PDF]
Umbilical cord blood (UBC) can be viewed as the most promising source of stem cells, in which collection cost is minimal and its benefits are immense. The cord blood is used to treat malignant and nonmalignant diseases; this is due to its progenitor characteristics know as stem cells.Its properties of being, immunologically immature and high plasticity
arxiv
Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4+ T-cell reconstitution [PDF]
Omission of in vivo T-cell depletion promotes rapid, thymic-independent CD4+-biased T-cell recovery after cord blood transplant. This enhanced T-cell reconstitution differs from that seen after stem cell transplant from other stem cell sources, but the ...
Amrolia, PJ+7 more
core
Cardiac troponin T in cord blood [PDF]
Perinatal asphyxia is associated with cardiac dysfunction. This may be secondary to myocardial ischaemia. Cardiac troponin T is the ideal marker for myocardial necrosis. Elevated levels in cord blood may be associated with intrauterine hypoxia and increased perinatal morbidity.To establish an upper limit of normal for cardiac troponin T concentration ...
Paul Newland+3 more
openaire +2 more sources