Results 91 to 100 of about 9,908 (255)

Enhancing cancer immunotherapy using cordycepin and Cordyceps militaris extract to sensitize cancer cells and modulate immune responses

open access: yesScientific Reports
Integrating immunotherapy with natural compounds holds promise in enhancing the immune system’s ability to eliminate cancer cells. Cordyceps militaris, a traditional Chinese medicine, emerges as a promising candidate in this regard.
Chutamas Thepmalee   +8 more
semanticscholar   +1 more source

Cordycepin-induced Keratinocyte Secretome Promotes Skin Cell Regeneration

open access: yesIn Vivo, 2023
Skin regeneration is the intrinsic ability to repair damaged skin tissues to regaining skin well-being. Processes of wound healing, a major part of skin regeneration, involve various types of cells, including keratinocytes and dermal fibroblasts, through their autocrine/paracrine signals.
Phongsakorn, Kunhorm   +2 more
openaire   +2 more sources

Efficacy of Cordyceps militaris Polysaccharides in Ameliorating Alcoholic Liver Injury and Modulating Gut Microbiota

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Our results suggest that Cordyceps militaris polysaccharide (CMP) can prevent alcohol‐induced oxidative stress and intestinal microbiota disorder, which may be related to the intestinal microbiota‐oxidative stress‐liver axis. ABSTRACT Alcoholic liver disease (ALD) is an inflammatory liver disorder caused by factors such as chronic excessive alcohol ...
Shi‐Rui Lu   +8 more
wiley   +1 more source

Matrix-assisted laser desorption ionization mass spectrometry based quantitative analysis of cordycepin from Cordyceps militaris

open access: yesJournal of Pharmaceutical Analysis, 2021
Cordycepin, which has great immunomodulatory activities such as anticancer, antifungal, antivirus, antileukemia and lipid-lowering ones, is the secondary metabolite of Cordyceps militaris (C. militaris).
Jian Chen   +4 more
doaj   +1 more source

Cleavage of 3′-terminal adenosine by archaeal ATP-dependent RNA ligase [PDF]

open access: yes, 2017
Methanothermobacter thermoautotrophicus RNA ligase (MthRnl) catalyzes formation of phosphodiester bonds between the 5′-phosphate and 3′-hydroxyl termini of single-stranded RNAs.
Gollnick Paul   +3 more
core   +3 more sources

Cordyceps militaris Extract and Cordycepin Alleviate Oxidative Stress, Modulate Gut Microbiota and Ameliorate Intestinal Damage in LPS-Induced Piglets

open access: yesAntioxidants
Cordycepin is considered a major bioactive component in Cordyceps militaris extract. This study was performed to evaluate the ameliorative effect of Cordyceps militaris extract (CME) and cordycepin (CPN) supplementation on intestinal damage in LPS ...
Shijie Xiong   +8 more
semanticscholar   +1 more source

Hepatoprotective Effect of Morchella Mycelia Polysaccharides on Alcoholic Liver Injury and Its Mechanism Involving the Modulation of NOD‐Like Receptor Signaling Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
The Morchella mycelium polysaccharide (MP), a homogeneous α‐glucan (96.555% glucose, 5.7 kDa), protects against alcohol‐induced liver injury in mice. It reduces serum ALT/AST, improves lipid metabolism, and enhances antioxidants and inhibiting lipid peroxidation. Mechanistically, the MP suppresses Nlrp3 inflammasome‐mediated inflammation/pyroptosis and
Xinyu Hu   +10 more
wiley   +1 more source

Inhibition of Leydig Cell Steroidogenesis: Effect of Actinomycin D Before and After Preincubation of Leydig Cells In Vitro [PDF]

open access: yes, 1978
The effect of preincubating purified Leydig cells in Eagle's medium and the subsequent effect of the mRNA synthesis inhibitor actinomycin D on LH‐stimulated testosterone synthesis has been investigated.
Cooke, B.A.   +2 more
core   +2 more sources

Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 1, January 2026.
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin   +3 more
wiley   +1 more source

Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway

open access: yesCancer Cell International, 2021
Background Osteosarcoma is the most common primary bone tumor in children and adolescents. However, some patients with osteosarcoma develop resistance to chemotherapy, leading to a poor clinical prognosis.
Hong-Bo Li   +6 more
doaj   +1 more source

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