Cordycepin in Schizosaccharomyces pombe: effects on the wild type and phenotypes of mutants resistant to the drug [PDF]
, 2018 The adenosine analogue cordycepin (3′-deoxyadenosine) inhibits growth and causes aberrant cell morphology in the fission yeast, Schizosaccharomyces pombe.
Hilti, N. +3 more
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Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo [PDF]
, 2016 Ribonucleotides are the most abundant non-canonical component of yeast genomic DNA and their persistence is associated with a distinctive mutation signature characterized by deletion of a single repeat unit from a short tandem repeat.
Burgers, Peter M +5 more
core +2 more sources
Synchronization of MEL cell commitment with cordycepin
Cell, 1979 The response of differentiating MEL cells to the nucleotide analogue cordycepin reveals a previously unrecognized aspect of the molecular events which cause commitment of these cells to terminal erythroid differentiation. Cordycepin rapidly inhibits commitment of DMSO-treated MEL cells in a dose range which does not cause cytotoxicity.
R, Levenson, J, Kernen, D, Housman
openaire +2 more sources
The Arabidopsis deNADding Enzyme DXO1 Modulates the Plant Immunity Response
Plant, Cell &Environment, Volume 49, Issue 1, Page 32-50, January 2026.ABSTRACT DXO1, the only DXO homolog in Arabidopsis, due to its plant‐specific features, exhibits strong deNADding enzymatic activity but has no apparent role in 5′ QC. Despite its important contribution to plant RNA metabolism, the direct impact of DXO1 enzymatic activity on cellular processes appears surprisingly limited.
Anna Golisz‐Mocydlarz +7 more
wiley +1 more source
Protective Effect of Cordycepin on Experimental Testicular Ischemia/Reperfusion Injury in Rats
Journal of Investigative Surgery, 2018 Objective: To investigate the role of cordycepin in testicular ischemia/reperfusion injury in rats. Materials and methods: Forty Wistar albino rats were randomly divided into four groups, as follows: group one, control (C); group two, torsion and ...
Mehmet Hanifi Okur +7 more
doaj +1 more source
The biotechnology of higher fungi - current state and perspectives [PDF]
, 2014 This review article concisely describes methodology of biotechnological processes with the use of cultures of higher fungi, their application in bioremediation and to obtain biologically active preparations.
Turło, Jadwiga
core +2 more sources
Structural and pharmacological insights into cordycepin for neoplasms and metabolic disorders
Frontiers in PharmacologyCytotoxic adenosine analogues were among the earliest chemotherapeutic agents utilised in cancer treatment. Cordycepin, a natural derivative of adenosine discovered in the fungus Ophiocordyceps sinensis, directly inhibits tumours not only by impeding ...
Jinming Zhang +3 more
semanticscholar +1 more source
Advanced Science, Volume 12, Issue 47, December 18, 2025.This review summarizes the design principles and key features of programmable hydrogels that respond to multiple stimuli. It then delves into the cutting‐edge mechanisms of self‐executing systems, highlighting their role as the cornerstone of next‐generation programmable hydrogels (NGPHs).
Guangli Xiang +8 more
wiley +1 more source
Cordycepin reduces weight through regulating gut microbiota in high-fat diet-induced obese rats
Lipids in Health and Disease, 2018 Background An increasing number of studies have shown that obesity is the key etiological agent of cardiovascular diseases, nonalcoholic fatty liver disease, type 2 diabetes and several kinds of cancer and that gut microbiota change was one of the ...
Yanan An +12 more
doaj +1 more source
Production of Insect Toxin Beauvericin From Entomopathogenic Fungi Cordyceps Militaris by Heterologous Expression of Global Regulator [PDF]
, 2018 Cordyceps militaris is one of entomopathogenic fungi species that is well known to be a traditional medicine in China for decades. Although the pharmaceutical and/or toxic properties of C.
Kinoshita, H. (Hiroshi) +2 more
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