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Cordycepin: A review of strategies to improve the bioavailability and efficacy
Phytotherapy Research, 2023Cordycepin is a bioactive compound extracted from Cordyceps militaris. As a natural antibiotic, cordycepin has a wide variety of pharmacological effects.
Min Chen +5 more
semanticscholar +1 more source
Life Science, 2023
Cholangiocarcinoma (CCA) with a high malignancy is usually diagnosed as advanced and is prone to metastasis and leads to a poor prognosis. It is reported that cordycepin has anti-tumor effect.
Xue-Fang Zhou +9 more
semanticscholar +1 more source
Cholangiocarcinoma (CCA) with a high malignancy is usually diagnosed as advanced and is prone to metastasis and leads to a poor prognosis. It is reported that cordycepin has anti-tumor effect.
Xue-Fang Zhou +9 more
semanticscholar +1 more source
ANTITUMOUR ACTIVITY OF CORDYCEPIN IN MICE
Clinical and Experimental Pharmacology and Physiology, 2004SUMMARY1. The antitumour effect of orally administered cordycepin, a component isolated from water extracts of Cordyceps sinensis, was examined in mice inoculated with B16 melanoma (B16‐BL6) cells.2. B16‐BL6 (1 × 106) cells were inoculated subcutaneously into the right footpad of mice.
Noriko, Yoshikawa +5 more
openaire +2 more sources
Free Radical Biology & Medicine
Parkinson's disease (PD) is a prevalent progressive and multifactorial neurodegenerative disorder. Cordycepin is known to exhibit antitumor, anti-inflammatory, antioxidative stress, and neuroprotective effects; however, few studies have explored the ...
Linhai Wang +12 more
semanticscholar +1 more source
Parkinson's disease (PD) is a prevalent progressive and multifactorial neurodegenerative disorder. Cordycepin is known to exhibit antitumor, anti-inflammatory, antioxidative stress, and neuroprotective effects; however, few studies have explored the ...
Linhai Wang +12 more
semanticscholar +1 more source
ACS Synthetic Biology, 2023
As the first nucleoside antibiotic discovered in fungi, cordycepin, with its various biological activities, has wide applications. At present, cordycepin is mainly obtained from the natural fruiting bodies of Cordyceps militaris.
Zeqi Song +9 more
semanticscholar +1 more source
As the first nucleoside antibiotic discovered in fungi, cordycepin, with its various biological activities, has wide applications. At present, cordycepin is mainly obtained from the natural fruiting bodies of Cordyceps militaris.
Zeqi Song +9 more
semanticscholar +1 more source
Biochemical Pharmacology
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) keeps rising with only a few drugs available. The present study aims to investigate the effects and mechanisms of cordycepin on MASLD.
Hai-Ying Tian +13 more
semanticscholar +1 more source
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) keeps rising with only a few drugs available. The present study aims to investigate the effects and mechanisms of cordycepin on MASLD.
Hai-Ying Tian +13 more
semanticscholar +1 more source
Synthesis, antitumor and antibacterial activities of cordycepin derivatives
Journal of Asian Natural Products Research, 2021Twelve novel cordycepin derivatives were designed and synthesized with modification at positions of 2', 5'-hydroxyl and N6 amino groups of cordycepin. The results showed that the inhibitory activities of 3, 4b, 6c and 6d on A549 were comparable to the positive control gefitinib, and the inhibitory activity of 6a on A549 was better than that of ...
Yu-Ting, Jin +7 more
openaire +2 more sources
Phytomedicine, 2023
BACKGROUND Parkinson's disease (PD), the most common neurodegenerative disorder, primarily affects dopaminergic neurons in the substantia nigra (SN). In addition to severe motor dysfunction, PD patients appear apparent cognitive impairments in the late ...
Shuqi Huang +7 more
semanticscholar +1 more source
BACKGROUND Parkinson's disease (PD), the most common neurodegenerative disorder, primarily affects dopaminergic neurons in the substantia nigra (SN). In addition to severe motor dysfunction, PD patients appear apparent cognitive impairments in the late ...
Shuqi Huang +7 more
semanticscholar +1 more source
International Immunopharmacology, 2023
The strategy of using immune checkpoint inhibitors (ICIs) has revolutionized cancer treatment, leading to remarkable clinical outcomes. However, certain cancer types and patient demographics continue to face unique challenges. As a result, it is vital to
Lujun Chen +11 more
semanticscholar +1 more source
The strategy of using immune checkpoint inhibitors (ICIs) has revolutionized cancer treatment, leading to remarkable clinical outcomes. However, certain cancer types and patient demographics continue to face unique challenges. As a result, it is vital to
Lujun Chen +11 more
semanticscholar +1 more source
Particle and Fibre Toxicology
Plastic pollution is an emerging environmental issue, with microplastics and nanoplastics raising health concerns due to bioaccumulation. This work explored the impact of polystyrene nanoparticle (PS-NPs) exposure during prepuberty on male reproductive ...
Ying Hu +6 more
semanticscholar +1 more source
Plastic pollution is an emerging environmental issue, with microplastics and nanoplastics raising health concerns due to bioaccumulation. This work explored the impact of polystyrene nanoparticle (PS-NPs) exposure during prepuberty on male reproductive ...
Ying Hu +6 more
semanticscholar +1 more source